Publication Name	World Journal of Gastroenterology
Manuscript ID	30557
Country	United States

Received	2016-10-08 08:30
Peer-Review Started	2016-10-09 20:16
To Make the First Decision	2016-11-09 08:14
Return for Revision	2016-11-11 16:35
Revised	2016-12-08 04:17
Second Decision	2016-12-16 17:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-12-21 16:14
Articles in Press	2016-12-21 16:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-02-08 15:04
Publish the Manuscript Online	2017-02-20 17:58

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Esophagogastric junction distensibility assessed using the functional lumen imaging probe
Manuscript Source	Unsolicited Manuscript
All Author List	Joan W Chen and Joel H Rubenstein
Funding Agency and Grant Number
Corresponding Author	Joan W Chen, MD, MS, Department of Gastroenterology and Hepatology, University of Michigan Health Systems, 3912 Taubman Center, 1500 E. Medical Center Dr., SPC 5362, Ann Arbor, MI 48109, United States. chenjoan@med.umich.edu
Key Words	Impedance planimetry; Gastroesophageal reflux disease; Esophageal distensibility; Achalasia
Core Tip	Functional lumen imaging probe (FLIP) uses impedance planimetry to calculate the distensibility of a hollow organ. In this systematic review, we aimed to assess FLIP reference values for gastroesophageal junction distensibility in healthy and diseased states. We found available normative data to vary widely. In achalasia, patients uniformly demonstrated low distensibility that improved after treatment, highlighting the role of FLIP in assessment of achalasia treatment efficacy. In gastroesophageal reflux disease, dis-tensibility fell to the range of untreated achalasia following fundoplication, emphasizing the importance of pre-operative screening for esophageal body dysmotililty. Future studies using a standardized FLIP protocol and balloon size are needed.
Publish Date	2017-02-20 17:58
Citation	Chen JW, Rubenstein JH. Esophagogastric junction distensibility assessed using the functional lumen imaging probe. World J Gastroenterol 2017; 23(7): 1289-1297
URL	http://www.wjgnet.com/1007-9327/full/v23/i7/1289.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i7.1289

Full Article (PDF)	WJG-23-1289.pdf
Full Article (Word)	WJG-23-1289.doc
Manuscript File	30557-Review.docx
Answering Reviewers	30557-Answering reviewers.pdf
Audio Core Tip	30557-Audio core tip.mp3
Biostatistics Review Certificate	30557-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	30557-Conflict-of-interest statement.pdf
Copyright License Agreement	30557-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	30557-Institutional review board statement.pdf
Peer-review Report	30557-Peer-review(s).pdf
Scientific Misconduct Check	30557-Scientific misconduct check.pdf
Scientific Editor Work List	30557-Scientific editor work list.pdf