Publication Name	World Journal of Hepatology
Manuscript ID	30559
Country	United States

Received	2016-10-08 08:28
Peer-Review Started	2016-10-12 10:55
To Make the First Decision	2016-11-11 09:35
Return for Revision	2016-11-17 15:12
Revised	2016-12-10 06:11
Second Decision	2017-02-09 18:17
Accepted by Journal Editor-in-Chief	2017-02-09 23:28
Accepted by Executive Editor-in-Chief	2017-02-20 15:13
Articles in Press	2017-02-20 15:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-03-20 10:29
Publish the Manuscript Online	2017-03-24 09:18

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Transplantation
Manuscript Type	Case Report
Article Title	Case of hepatocellular carcinoma in a patient with hereditary tyrosinemia in the post-newborn screening era
Manuscript Source	Invited Manuscript
All Author List	Essam M Imseis, John S Bynon and Chad Thornhill
Funding Agency and Grant Number
Corresponding Author	Essam M Imseis, MD, Department of Pediatrics, Gastroenterology Division, the University of Texas Health Science Center at Houston, Houston McGovern Medical School, 6431 Fannin St., MSB 3.137, Houston, TX 77030, United States. essam.imseis@uth.tmc.edu
Key Words	Tyrosinemia; Screening; Hepatocellular carcinoma; Liver transplantation
Core Tip	Hereditary tyrosinemia type 1 is a metabolic defect resulting in several disease manifestations in-cluding life threatening hepatorenal disease, neurologic disease, and rickets. Although neonatal screening for this disorder has allowed early identification and medical treatment with nitisinone, the need for recognition of this disorder in older individuals remains since aggressive intervention, including medical treatment and possible liver transplantation, may be lifesaving and have profound effects on morbidity and mortality.
Publish Date	2017-03-24 09:18
Citation	Imseis EM, Bynon JS, Thornhill C. Case of hepatocellular carcinoma in a patient with hereditary tyrosinemia in the post-newborn screening era. World J Hepatol 2017; 9(9): 487-490
URL	http://www.wjgnet.com/1948-5182/full/v9/i9/487.htm
DOI	http://dx.doi.org/10.4254/wjh.v9.i9.487

Full Article (PDF)	WJH-9-487.pdf
Full Article (Word)	WJH-9-487.doc
Manuscript File	30559-Review.docx
Answering Reviewers	30559-Answering reviewers.pdf
Audio Core Tip	30559-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	30559-Conflict-of-interest statement.pdf
Copyright License Agreement	30559-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	30559-Institutional review board statement.pdf
Peer-review Report	30559-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	30559-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	30559-Scientific misconduct check.pdf
Scientific Editor Work List	30559-Scientific editor work list.pdf