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5/6/2017 8:30:21 PM | Browse: 61 | Download: 184
Publication Name World Journal of Gastroenterology
Manuscript ID 30672
Country of Manuscript Source China
Received
2016-10-13 09:21
Peer-Review Started
2016-10-14 08:25
To Make the First Decision
2016-12-28 17:26
Return for Revision
2016-12-29 10:32
Revised
2017-01-16 21:47
Second Decision
2017-02-15 19:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-02-17 10:11
Articles In Press
2017-02-17 10:11
Publication Fee Transferred
Edit the Manuscript by Languag Editor
2017-03-29 16:41
Typeset the Manuscript
2017-04-24 14:26
Publish the Manuscript Online
2017-05-06 20:30
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Specialty Surgery
Manuscript Type Retrospective Study
Article Title Prognostic value of the neutrophil-to-lymphocyte ratio for hepatocellular carcinoma patients with portal/hepatic vein tumor thrombosis
Manuscript Source Unsolicited Manuscript
All Author List Shao-Hua Li, Qiao-Xuan Wang, Zhong-Yuan Yang, Wu Jiang, Cong Li, Peng Sun, Wei Wei, Ming Shi and Rong-Ping Guo
Funding Agency and Grant Number
Correspondence To Rong-Ping Guo, MD, Department of Hepatobiliary Surgery, Cancer Center of Sun Yat-Sen University, 651 Dongfeng East Road, Guangzhou 510275, Guangdong Province, China. guorp@sysucc.org.cn
Keywords Hepatocellular carcinoma; Portal/hepatic vein tumor thrombosis; Neutrophil-to-lymphocyte ratio; Prognosis
Core Tip The systemic inflammatory response generated by tumors has been shown to cause the upregulation of cytokines and inflammatory mediators, leading to the promotion of angiogenesis and DNA damage and the inhibition of apoptosis. The presence of a systemic inflammatory response can be detected by the elevation of the neutrophil-to-lymphocyte ratio (NLR), which has been shown to be associated with poorer prognosis in patients with various types of malignant tumors. Our findings confirm that the NLR can be used as a potential prognostic predictor for hepatocellular carcinoma patients with portal/hepatic vein tumor thrombosis after resection. The results of the present study may help identify a new serum marker for predicting the post-operation survival of these patients.
Publish Date 2017-05-06 20:30
Citation Li SH, Wang QX, Yang ZY, Jiang W, Li C, Sun P, Wei W, Shi M, Guo RP. Prognostic value of the neutrophil-to-lymphocyte ratio for hepatocellular carcinoma patients with portal/hepatic vein tumor thrombosis. World J Gastroenterol 2017; 23(17): 3122-3132
Url http://www.wjgnet.com/1007-9327/full/v23/i17/3122.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i17.3122
Full Article (PDF) WJG-23-3122.pdf
Full Article (Word) WJG-23-3122.doc
Revised Manuscript 30672-Review.docx
Peer-review Report 30672-Peer-review(s).pdf
Answering Reviewers 30672-Answering reviewers.pdf
Scientific Misconduct Check 30672-Scientific misconduct check.pdf
Scientific Editor Work List 30672-Scientific editor work list.pdf
Audio 30672-Audio core tip.mp3
Biostatistics Statement 30672-Biostatistics statement.pdf
Conflict-of-Interest Statement 30672-Conflict-of-interest statement.pdf
Copyright Assignment 30672-Copyright assignment.PDF
Data Sharing Statement 30672-Data sharing statement.pdf
Institutional Review Board Statement 30672-Institutional review board statement.pdf
Scientific Research Process 30672-Scientific research process.pdf