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Articles Published Processes
1/22/2017 11:39:00 AM | Browse: 1422 | Download: 2575
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Received |
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2016-10-13 10:21 |
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Peer-Review Started |
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2016-10-14 08:03 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2016-12-02 17:15 |
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Revised |
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2016-12-15 23:31 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2016-12-29 10:49 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2017-01-04 16:30 |
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Articles in Press |
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2017-01-04 16:30 |
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Edit the Manuscript by Language Editor |
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2017-01-09 05:55 |
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Typeset the Manuscript |
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2017-01-13 12:31 |
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Publish the Manuscript Online |
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2017-01-22 11:39 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Effects of sex and generation on hepatitis B viral load in families with hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ai-Ru Hsieh, Cathy SJ Fann, Chau-Ting Yeh, Hung-Chun Lin, Shy-Yi Wan, Yi-Cheng Chen, Chia-Lin Hsu, Jennifer Tai, Shi-Ming Lin and Dar-In Tai |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chang Gung Memorial Hospital |
CMRPG3C0701 |
| the National Science Council |
NSC101-2314-B-182A-025-MY3 |
| China Medical University |
CMU103-N-15 |
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| Corresponding Author |
Dar-In Tai, MD, Professor, Division of Hepatology, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, No 5, FuXing Street, Guishan Dist., Taoyuan 333, Taiwan. tai48978@cgmh.org.tw |
| Key Words |
Familial generation; Sex; Hepatitis B virus; Perinatal infection; Viral replication |
| Core Tip |
Familial clustering of chronic hepatitis B infection is identified in this study. Most of the hepatitis B surface antigen (HBsAg) carriers in this cohort are in families of an HBsAg-positive index case. A high prevalence of HBsAg is found in the siblings’ generation and in offspring of an HBsAg-positive mother. The HBsAg status of index cases and HBsAg status of the mother are important factors for determining the persistence of hepatitis B virus (HBV) infection in hepatocellular carcinoma families. Sex and generation are factors associated with HBV replication. Perinatal infection has a great influence on male offspring’s HBV replication. |
| Publish Date |
2017-01-22 11:39 |
| Citation |
Hsieh AR, Fann CSJ, Yeh CT, Lin HC, Wan SY, Chen YC, Hsu CL, Tai J, Lin SM, Tai DI. Effects of sex and generation on hepatitis B viral load in families with hepatocellular carcinoma. World J Gastroenterol 2017; 23(5): 876-884 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i5/876.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i5.876 |
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