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Articles Published Processes
3/13/2017 7:05:00 PM | Browse: 837 | Download: 1455
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Received |
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2016-10-21 17:31 |
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Peer-Review Started |
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2016-10-25 08:43 |
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To Make the First Decision |
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2016-12-28 17:26 |
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Return for Revision |
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2016-12-29 10:37 |
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Revised |
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2017-01-03 12:12 |
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Second Decision |
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2017-01-16 13:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-01-17 16:59 |
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Articles in Press |
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2017-01-17 17:00 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-02-09 12:09 |
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Typeset the Manuscript |
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2017-03-01 12:44 |
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Publish the Manuscript Online |
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2017-03-13 19:06 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Serum HER2 as a predictive biomarker for tissue HER2 status and prognosis in patients with gastric cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hong-Zhi Shi, Yu-Ning Wang, Xiao-Hui Huang, Ke-Cheng Zhang, Hong-Qing Xi, Jian-Xin Cui, Guo-Xiao Liu, Wen-Tao Liang, Bo Wei and Lin Chen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81272698 |
| National Natural Science Foundation of China |
81672319 |
| National Natural Science Foundation of China |
81602507 |
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| Corresponding Author |
Dr. Lin Chen, Department of General Surgery, Chinese PLA General Hospital, Fuxing Road 28, Beijing 100853, China. chenlinbj301@163.com
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| Key Words |
Gastric cancer; Serum HER2 extracellular domain; Tissue HER2 status; Prognosis |
| Core Tip |
Precise determination of HER2 status is crucial for the appropriate use of HER2-targeted therapy in gastric cancer patients. Our study investigated the association between serum HER2 extracellular domain (ECD) and tissue HER2 status, and also determined the prognostic value of serum HER2 ECD in a large cohort of patients. Serum HER2 ECD could provide an easily accessible surrogate marker for tissue HER2 status, with high specificity. Furthermore, high serum HER2 ECD had a negative impact on overall survival in patients with gastric cancer.
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| Publish Date |
2017-03-13 19:06 |
| Citation |
Shi HZ, Wang YN, Huang XH, Zhang KC, Xi HQ, Cui JX, Liu GX, Liang WT, Wei B, Chen L. Serum HER2 as a predictive biomarker for tissue HER2 status and prognosis in patients with gastric cancer. World J Gastroenterol 2017; 23(10): 1836-1842 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i10/1836.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i10.1836 |
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