Publication Name	World Journal of Gastroenterology
Manuscript ID	31057
Country	United States

Received	2016-10-28 09:20
Peer-Review Started	2016-10-28 15:03
To Make the First Decision	2016-12-01 15:42
Return for Revision	2016-12-02 17:20
Revised	2016-12-17 03:16
Second Decision	2016-12-29 10:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-01-04 16:31
Articles in Press	2017-01-04 16:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-02-07 14:58
Publish the Manuscript Online	2017-02-12 17:23

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Pathology
Manuscript Type	Case Report
Article Title	Coexisting tubular adenoma with a neuroendocrine carcinoma of colon allowing early surgical intervention and implicating a shared stem cell origin
Manuscript Source	Unsolicited Manuscript
All Author List	Mahmoud L Soliman, Ashish Tiwari and Qing Zhao
Funding Agency and Grant Number
Corresponding Author	Qing Zhao, MD, PhD, Assistant Professor, Department of Pathology and Laboratory Medicine, Boston University Medical Center, 670 Albany Street, 6th floor, Room 670, Boston, MA 02118, United States. grace.zhao@bmc.org
Key Words	Neuroendocrine carcinoma; Tubular adenoma; Colorectal; Colocalization
Core Tip	This is a case report of a patient with a high-grade large cell neuroendocrine carcinoma in the ascending colon with an overlying tubular adenoma discovered during routine colonoscopic screening in absence of clinical symptoms. This is a unique case where the contiguity of the neuroendocrine carcinoma to the tubular adenoma allowed for the diagnosis of the otherwise high-grade carcinoma. Being aware of this association bears practical implication where it can be conducive to the early and correct diagnosis of invasive cancer. In addition, we review the literature citing pertinent cases.
Publish Date	2017-02-12 17:23
Citation	Soliman ML, Tiwari A, Zhao Q. Coexisting tubular adenoma with a neuroendocrine carcinoma of colon allowing early surgical intervention and implicating a shared stem cell origin. World J Gastroenterol 2017; 23(6): 1106-1112
URL	http://www.wjgnet.com/1007-9327/full/v23/i6/1106.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i6.1106

Full Article (PDF)	WJG-23-1106.pdf
Full Article (Word)	WJG-23-1106.doc
Manuscript File	31057-Review.docx
Answering Reviewers	31057-Answering reviewers.pdf
Audio Core Tip	31057-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	31057-Conflict-of-interest statement.pdf
Copyright License Agreement	31057-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	31057-Institutional review board statement.pdf
Peer-review Report	31057-Peer-reivew(s).pdf
Scientific Misconduct Check	31057-Scientific misconduct check.pdf
Scientific Editor Work List	31057-Scientific editor work list.pdf