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Articles Published Processes
5/6/2017 8:30:21 PM | Browse: 1137 | Download: 1764
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Received |
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2016-11-05 12:15 |
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Peer-Review Started |
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2016-11-21 16:51 |
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To Make the First Decision |
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2016-12-28 17:27 |
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Return for Revision |
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2017-01-03 14:52 |
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Revised |
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2017-03-03 00:00 |
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Second Decision |
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2017-03-09 17:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-03-15 13:33 |
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Articles in Press |
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2017-03-15 13:34 |
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Publication Fee Transferred |
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2017-04-07 17:30 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-04-25 09:18 |
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Publish the Manuscript Online |
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2017-05-06 20:30 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Prospective Study |
Article Title |
Cost-effectiveness of enhanced liver fibrosis test to assess liver fibrosis in chronic hepatitis C virus and alcoholic liver disease patients
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Marcelo Soto, Laura Sampietro-Colom, Luis Lasalvia, Aurea Mira, Wladimiro Jiménez and Miquel Navasa |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Siemens. Marcelo Soto received financial support from Plataforma ITEMAS PT13/0006/0009 (FCRB PI043029, partially) |
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Corresponding Author |
Dr. Marcelo Soto, Fundació Clínic per a la Recerca Biomèdica, Roselló 149-153, 08036 Barcelona, Spain. soto@clinic.ub.es |
Key Words |
Cost-effectiveness analysis; Liver fibrosis; Noninvasive diagnostic assessment; Alcoholic liver disease; Hepatitis C |
Core Tip |
Noninvasive methods to diagnose liver fibrosis have been proposed as an alternative to liver biopsy in patients with abnormal level of transaminases. In a Markov model, sequential testing with enhanced liver fibrosis (ELF) test followed by liver stiffness measurement (LSM) significantly reduce liver-related lifetime morbidity and mortality, compared with biopsy, in hepatitis C virus (HCV) and alcoholic liver disease patients. Noninvasive methods are also associated with an increase in quality-adjusted life years and costs. Overall, they are cost-effective strategies compared with biopsy. ELF test with or without a confirmation LSM may represent a more affordable strategy than the “treat-all” option in HCV patients. |
Publish Date |
2017-05-06 20:30 |
Citation |
Soto M, Sampietro-Colom L, Lasalvia L, Mira A, Jiménez W, Navasa M. Cost-effectiveness of enhanced liver fibrosis test to assess liver fibrosis in chronic hepatitis C virus and alcoholic liver disease patients. World J Gastroenterol 2017; 23(17): 3163-3173 |
URL |
http://www.wjgnet.com/1007-9327/full/v23/i17/3163.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v23.i17.3163 |
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