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Publication Name World Journal of Gastroenterology
Manuscript ID 31218
Country/Territory Spain
2016-11-05 12:15
Peer-Review Started
2016-11-21 16:51
To Make the First Decision
2016-12-28 17:27
Return for Revision
2017-01-03 14:52
2017-03-03 00:00
Second Decision
2017-03-09 17:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-03-15 13:33
Articles in Press
2017-03-15 13:34
Publication Fee Transferred
2017-04-07 17:30
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-04-25 09:18
Publish the Manuscript Online
2017-05-06 20:30
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Prospective Study
Article Title Cost-effectiveness of enhanced liver fibrosis test to assess liver fibrosis in chronic hepatitis C virus and alcoholic liver disease patients
Manuscript Source Unsolicited Manuscript
All Author List Marcelo Soto, Laura Sampietro-Colom, Luis Lasalvia, Aurea Mira, Wladimiro Jiménez and Miquel Navasa
Funding Agency and Grant Number
Funding Agency Grant Number
Siemens. Marcelo Soto received financial support from Plataforma ITEMAS PT13/0006/0009 (FCRB PI043029, partially)
Corresponding author Dr. Marcelo Soto, Fundació Clínic per a la Recerca Biomèdica, Roselló 149-153, 08036 Barcelona, Spain. soto@clinic.ub.es
Keywords Cost-effectiveness analysis; Liver fibrosis; Noninvasive diagnostic assessment; Alcoholic liver disease; Hepatitis C
Core Tip Noninvasive methods to diagnose liver fibrosis have been proposed as an alternative to liver biopsy in patients with abnormal level of transaminases. In a Markov model, sequential testing with enhanced liver fibrosis (ELF) test followed by liver stiffness measurement (LSM) significantly reduce liver-related lifetime morbidity and mortality, compared with biopsy, in hepatitis C virus (HCV) and alcoholic liver disease patients. Noninvasive methods are also associated with an increase in quality-adjusted life years and costs. Overall, they are cost-effective strategies compared with biopsy. ELF test with or without a confirmation LSM may represent a more affordable strategy than the “treat-all” option in HCV patients.
Publish Date 2017-05-06 20:30
Citation Soto M, Sampietro-Colom L, Lasalvia L, Mira A, Jiménez W, Navasa M. Cost-effectiveness of enhanced liver fibrosis test to assess liver fibrosis in chronic hepatitis C virus and alcoholic liver disease patients. World J Gastroenterol 2017; 23(17): 3163-3173
Url http://www.wjgnet.com/1007-9327/full/v23/i17/3163.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i17.3163
Full Article (PDF) WJG-23-3163.pdf
Full Article (Word) WJG-23-3163.doc
Manuscript File 31218-Review.docx
Answering Reviewers 31218-Answering reviewers.pdf
Audio Core Tip 31218-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 31218-Conflict-of-interest statement.pdf
Copyright License Agreement 31218-Copyright assignment.pdf
Supplementary Material 31218-Supplementary material.docx
Peer-review Report 31218-Peer-review(s).pdf
Scientific Misconduct Check 31218-Scientific misconduct check.pdf
Scientific Editor Work List 31218-Scientific editor work list.pdf