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2/17/2017 8:32:00 AM | Browse: 607 | Download: 508
Publication Name World Journal of Hepatology
Manuscript ID 31403
Country of Manuscript Source Turkey
Received
2016-11-15 09:24
Peer-Review Started
To Make the First Decision
2016-11-18 14:06
Return for Revision
2016-11-18 15:13
Revised
2016-11-22 19:52
Second Decision
2016-12-02 08:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-12-09 18:08
Articles in Press
2016-12-09 18:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
2016-12-20 06:03
Typeset the Manuscript
2017-02-14 08:09
Publish the Manuscript Online
2017-02-17 08:32
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Review
Article Title Adverse effects of oral antiviral therapy in chronic hepatitis B
Manuscript Source Invited Manuscript
All Author List Bircan Kayaaslan and Rahmet Guner
Funding Agency and Grant Number
Corresponding author Bircan Kayaaslan, MD, Department of Infectious Disease and Clinical Microbiology, Yildirim Beyazit University Faculty of Medicine, Ataturk Education and Research Hospital, Bilkent Street no: 1, 06800 Ankara, Turkey. drbican@gmail.com
Keywords Nucleoside/nucleotide analogues; Adverse events; Lamivudine; Chronic hepatitis B; Side effects; Safety; Telbivudine; Hepatitis B infection; Adefovir; Entecavir; Adverse effects; Tenofovir; Hepatitis B virus
Core Tip Extrahepatic effects of nucleotide analogues (i.e., myopathy, nephropathy, bone disorders) are more commonly indicated in current reports. Some of these adverse events can be attributed to their effect of causing mitochondrial dysfunction. These adverse events are named as “class effects” and mostly associated with lamivudine and telbivudine treatment. Adefovir is a well-known nephrotoxic agent. Nephrotoxic and bone density loss effects of tenofovir in patients with chronic hepatitis B (CHB) are not as clear as in those with human immunodeficiency virus infection. Serum creatinine, phosphorus and creatine kinase levels should be monitored. Safety profile is a major issue that should not be ignored in the treatment of CHB.
Publish Date 2017-02-17 08:32
Citation Kayaaslan B, Guner R. Adverse effects of oral antiviral therapy in chronic hepatitis B. World J Hepatol 2017; 9(5): 227-241
Url http://www.wjgnet.com/1948-5182/full/v9/i5/227.htm
DOI http://dx.doi.org/10.4254/wjh.v9.i5.227
Full Article (PDF) WJH-9-227.pdf
Full Article (Word) WJH-9-227.doc
Manuscript File 31403-Review.docx
Answering Reviewers 31403-Answering reviewers.pdf
Audio Core Tip 31403-Audio core tip.3gp
Conflict-of-Interest Disclosure Form 31403-Conflict-of-interest statement.pdf
Copyright License Agreement 31403-Copyright assignment.pdf
Peer-review Report 31403-Peer-review(s).pdf
Scientific Misconduct Check 31403-Scientific misconduct check.pdf
Scientific Editor Work List 31403-Scientific editor work list.pdf