| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Variability of anti-human transglutaminase testing in celiac disease across Mediterranean countries
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Andrea Smarrazzo, Giuseppe Magazzù, Mongi Ben-Hariz, Maria Legarda Tamara, Virtut Velmishi, Elefhteria Roma, Aydan Kansu, Dušanka Mičetić-Turk, Enzo Bravi, Pio Stellato, Carmela Arcidiaco and Luigi Greco |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Italian Department of Health, Direction of International Affairs |
|
| MEDICEL-Mediterranean Network for Celiac Disease–Phase II |
CUP n° E61J11000450001 |
| European Laboratory for Food Induced Disease, Federico II University, Naples |
|
|
| Corresponding Author |
Andrea Smarrazzo, MD, Department of Translational Medical Sciences, Section of Pediatrics, University of Naples “Federico II”, Via Sergio Pansini 5, 80131 Naples, Italy. and.smarrazzo@libero.it |
| Key Words |
Coeliac disease; Gluten; Transglutaminase; Non-invasive testing; Accuracy; Precision |
| Core Tip |
The “epidemic” of celiac disease (CD) across Mediterranean countries stimulated the need to standardize commonly used diagnostic tests. The titre of anti-transglutaminase antibodies has a strong relevance in the diagnosis of CD as defined by the ESPGHAN criteria; few studies, at the moment, estimated the variability of the main diagnostic tool for CD, in terms of accuracy and precision. Our study represents the first quality control work on this subject, with strong implication especially in countries with limited resources, where duodenal biopsy is not so easily performed. |
| Publish Date |
2017-06-26 10:23 |
| Citation |
Smarrazzo A, Magazzù G, Ben-Hariz M, Legarda Tamara M, Velmishi V, Roma E, Kansu A, Mičetić-Turk D, Bravi E, Stellato P, Arcidiaco C, Greco L. Variability of anti-human transglutaminase testing in celiac disease across Mediterranean countries. World J Gastroenterol 2017; 23(24): 4437-4443 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i24/4437.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i24.4437 |
