Publication Name	World Journal of Orthopedics
Manuscript ID	31500
Country	United Kingdom

Received	2016-11-21 08:57
Peer-Review Started	2016-11-23 12:17
To Make the First Decision	2016-12-14 08:47
Return for Revision	2016-12-15 12:18
Revised	2016-12-21 06:26
Second Decision	2017-01-04 16:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-01-14 14:15
Articles in Press	2017-01-14 14:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-04-10 16:42
Publish the Manuscript Online	2017-04-17 19:22

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Systematic Reviews
Article Title	Total hip arthroplasty in patients with Paget’s disease of bone: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Sammy A Hanna, Sebastian Dawson-Bowling, Steven Millington, Rej Bhumbra and Pramod Achan
Funding Agency and Grant Number
Corresponding Author	Sammy A Hanna, MD (Res), FRCS (Tr and Orth), Department of Trauma and Orthopaedic Surgery, Royal London Hospital, Barts Health NHS Trust, Whitechapel Road, London E1 1BB, United Kingdom. sammy.hanna@bartshealth.nhs.uk
Key Words	Total hip arthroplasty; Paget’s disease; Revision; Loosening; Heterotopic ossification
Core Tip	Patients with Paget’s disease commonly develop structural bone deformities in the proximal femur, making total hip arthroplasty (THA) technically demanding. In addition, achieving adequate fixation of hip implants in the hypervascular and often sclerotic bone may prove challenging. This review has shown that, despite its challenging nature, THA can be very successful in terms of improving symptoms and restoring hip function in this unique group of patients. The failure rate, however, appears to be slightly higher than in other patients undergoing a primary total hip replacement. The most common reason for revision surgery is aseptic loosening, and using modern uncemented implants appear to reduce the risk of this occurring.
Publish Date	2017-04-17 19:22
Citation	Hanna SA, Dawson-Bowling S, Millington S, Bhumbra R, Achan P. Total hip arthroplasty in patients with Paget’s disease of bone: A systematic review. World J Orthop 2017; 8(4): 357-363
URL	http://www.wjgnet.com/2218-5836/full/v8/i4/357.htm
DOI	http://dx.doi.org/10.5312/wjo.v8.i4.357

Full Article (PDF)	WJO-8-357.pdf
Full Article (Word)	WJO-8-357.doc
Manuscript File	31500-Review.docx
Answering Reviewers	31500-Answering reviewers.pdf
Audio Core Tip	31500-Audio core tip.mp3
Biostatistics Review Certificate	31500-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	31500-Conflict-of-interest statement.pdf
Copyright License Agreement	31500-Copyright assignment.pdf
Peer-review Report	31500-Peer-review(s).pdf
Scientific Misconduct Check	31500-Scientific misconduct check.pdf
Scientific Editor Work List	31500-Scientific editor work list.pdf