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5/18/2017 4:11:31 AM | Browse: 668 | Download: 495
Publication Name World Journal of Biological Chemistry
Manuscript ID 31747
Country of Manuscript Source United States
Received
2016-12-05 09:13
Peer-Review Started
2016-12-06 16:51
To Make the First Decision
2017-01-14 11:20
Return for Revision
2017-01-16 18:16
Revised
2017-02-08 14:36
Second Decision
2017-03-02 16:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-03-13 11:39
Articles in Press
2017-03-13 11:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-05-16 01:41
Publish the Manuscript Online
2017-05-18 04:11
ISSN 1949-8454 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Biochemistry and Molecular Biology
Manuscript Type Editorial
Article Title Common therapeutic target for both cancer and obesity
Manuscript Source Invited Manuscript
All Author List Yie-Hwa Chang
Funding Agency and Grant Number
Corresponding author Yie-Hwa Chang, Associate Professor of Edward A. Doisy Department of Biochemistry and Molecular Biology, Doisy Research Center, St. Louis University Medical School, 1100 S. Grand Blvd., St. Louis, MO 63104, United States. changyh@slu.edu
Keywords Methionine aminopeptidase; Angiogenesis; Cancer; Obesity; Diabetes; Protein processing; Protein stability; Protein maturation; Protein modification
Core Tip There were approximately 14 million new cancer cases worldwide each year and more than half of the population in the developed countries are overweight or obese. Obesity is responsible for nearly 25% of the relative contribution to cancer incidence, which ranks second only to tobacco use. It would be, therefore, highly desirable to have drugs that work for both cancer and obesity. In this article, the biological function of a common therapeutic target, methionine aminopeptidase-2, and the status of some of its inhibitors in pre-clinical and clinical trials for cancer and/or obesity were discussed.
Publish Date 2017-05-18 04:11
Citation Chang YH. Common therapeutic target for both cancer and obesity. World J Biol Chem 2017; 8(2): 102-107
Url http://www.wjgnet.com/1949-8454/full/v8/i2/102.htm
DOI http://dx.doi.org/10.4331/wjbc.v8.i2.102
Full Article (PDF) WJBC-8-102.pdf
Full Article (Word) WJBC-8-102.doc
Manuscript File 31747-Review.docx
Answering Reviewers 31747-Answering reviewers.pdf
Audio Core Tip 31747-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 31747-Conflict-of-interest statement.pdf
Copyright License Agreement 31747-Copyright assignment.pdf
Peer-review Report 31747-Peer-review(s).pdf
Scientific Misconduct Check 31747-Scientific misconduct check.pdf
Scientific Editor Work List 31747-Scientific editor work list.pdf