Publication Name	World Journal of Biological Chemistry
Manuscript ID	31747
Country	United States

Received	2016-12-05 09:13
Peer-Review Started	2016-12-06 16:51
To Make the First Decision	2017-01-14 11:20
Return for Revision	2017-01-16 18:16
Revised	2017-02-08 14:36
Second Decision	2017-03-02 16:18
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-03-13 11:39
Articles in Press	2017-03-13 11:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-05-16 01:41
Publish the Manuscript Online	2017-05-18 04:11

ISSN	1949-8454 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Biochemistry & Molecular Biology
Manuscript Type	Editorial
Article Title	Common therapeutic target for both cancer and obesity
Manuscript Source	Invited Manuscript
All Author List	Yie-Hwa Chang
Funding Agency and Grant Number
Corresponding Author	Yie-Hwa Chang, Associate Professor of Edward A. Doisy Department of Biochemistry and Molecular Biology, Doisy Research Center, St. Louis University Medical School, 1100 S. Grand Blvd., St. Louis, MO 63104, United States. changyh@slu.edu
Key Words	Methionine aminopeptidase; Angiogenesis; Cancer; Obesity; Diabetes; Protein processing; Protein stability; Protein maturation; Protein modification
Core Tip	There were approximately 14 million new cancer cases worldwide each year and more than half of the population in the developed countries are overweight or obese. Obesity is responsible for nearly 25% of the relative contribution to cancer incidence, which ranks second only to tobacco use. It would be, therefore, highly desirable to have drugs that work for both cancer and obesity. In this article, the biological function of a common therapeutic target, methionine aminopeptidase-2, and the status of some of its inhibitors in pre-clinical and clinical trials for cancer and/or obesity were discussed.
Publish Date	2017-05-18 04:11
Citation	Chang YH. Common therapeutic target for both cancer and obesity. World J Biol Chem 2017; 8(2): 102-107
URL	http://www.wjgnet.com/1949-8454/full/v8/i2/102.htm
DOI	http://dx.doi.org/10.4331/wjbc.v8.i2.102

Full Article (PDF)	WJBC-8-102.pdf
Full Article (Word)	WJBC-8-102.doc
Manuscript File	31747-Review.docx
Answering Reviewers	31747-Answering reviewers.pdf
Audio Core Tip	31747-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	31747-Conflict-of-interest statement.pdf
Copyright License Agreement	31747-Copyright assignment.pdf
Peer-review Report	31747-Peer-review(s).pdf
Scientific Misconduct Check	31747-Scientific misconduct check.pdf
Scientific Editor Work List	31747-Scientific editor work list.pdf