Publication Name	World Journal of Cardiology
Manuscript ID	31769
Country	United States

Received	2016-12-06 08:57
Peer-Review Started	2016-12-07 08:59
To Make the First Decision	2017-01-14 11:23
Return for Revision	2017-01-16 19:06
Revised	2017-01-27 00:45
Second Decision	2017-02-20 16:01
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-03-02 08:39
Articles in Press	2017-03-02 08:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-04-19 08:10
Publish the Manuscript Online	2017-04-28 09:52

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Basic Study
Article Title	Dissection of Z-disc myopalladin gene network involved in the development of restrictive cardiomyopathy using system genetics approach
Manuscript Source	Invited Manuscript
All Author List	Qingqing Gu, Uzmee Mendsaikhan, Zaza Khuchua, Byron C Jones, Lu Lu, Jeffrey A Towbin, Biao Xu and Enkhsaikhan Purevjav
Funding Agency and Grant Number	Funding Agency Grant Number NIH R01 HL128350 NIH R01 HL53392 NIH R01 HL087000
Corresponding Author	Enkhsaikhan Purevjav, MD, PhD, Department of Pediatrics, the Heart Institute, University of Ten¬nessee Health Science Center, 71 S Manassas Street, Memphis, TN 38103, United States. epurevja@uthsc.edu
Key Words	System genetics; Myopalladin; System pro¬teomics; Cardiomyopathy; Mutation
Core Tip	Myopalladin (Mypn) is one of genes associated with many types of familial cardiomyopathies including dilated, hypertrophic and restrictive cardiomyopathy (RCM). Using systematic genetics approach, we con¬structed Mypn co-expression networks of similarly regulated genes that function within defined biological processes. Several novel Mypn-interacting genes with potential important role in the development of RCM were discovered.
Publish Date	2017-04-28 09:52
Citation	Gu Q, Mendsaikhan U, Khuchua Z, Jones BC, Lu L, Towbin JA, Xu B, Purevjav E. Dissection of Z-disc myopalladin gene network involved in the development of restrictive cardiomyopathy using system genetics approach. World J Cardiol 2017; 9(4): 320-331
URL	http://www.wjgnet.com/1949-8462/full/v9/i4/320.htm
DOI	http://dx.doi.org/10.4330/wjc.v9.i4.320

Full Article (PDF)	WJC-9-320.pdf
Full Article (Word)	WJC-9-320.doc
Manuscript File	31769-Review.docx
Answering Reviewers	31769-Answering reviewers.pdf
Audio Core Tip	31769-Audio core tip.m4a
Biostatistics Review Certificate	31769-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	31769-Conflict-of-interest statement.pdf
Copyright License Agreement	31769-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	31769-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	31769-Institutional animal care and use committee statement.pdf
Peer-review Report	31769-Peer-review(s).pdf
Scientific Misconduct Check	31769-Scientific misconduct check.pdf
Scientific Editor Work List	31769-Scientific editor work list.pdf