Publication Name	World Journal of Gastroenterology
Manuscript ID	31854
Country	Italy

Received	2016-12-12 09:21
Peer-Review Started	2016-12-12 10:56
To Make the First Decision	2017-01-10 16:53
Return for Revision	2017-01-11 13:21
Revised	2017-01-20 20:07
Second Decision	2017-02-15 21:13
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-02-17 13:26
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-03-01 14:53
Publish the Manuscript Online	2017-03-13 19:06

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Medicine, Research & Experimental
Manuscript Type	Meta-Analysis
Article Title	Markers of systemic inflammation and colorectal adenoma risk: Meta-analysis of observational studies
Manuscript Source	Invited Manuscript
All Author List	Justyna Godos, Antonio Biondi, Fabio Galvano, Francesco Basile, Salvatore Sciacca, Edward L Giovannucci and Giuseppe Grosso
Funding Agency and Grant Number
Corresponding Author	Giuseppe Grosso, MD, PhD, Integrated Cancer Registry of Catania-Messina-Siracusa-Enna, Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele, 95123 Catania, Italy. giuseppe.grosso@studium.unict.it
Key Words	Inflammatory markers; Meta-analysis; Colorectal adenoma; C-reactive protein; Tumor necrosis factor-alpha; Interleukin-6
Core Tip	The present study investigated the asso-ciation between inflammatory markers and risk of colorectal adenoma. Ten studies on C-reactive protein (CRP) showed non-significant summary odds ratios in the general analysis. However, CRP was significantly correlated with increased risk of advanced adenoma. Subgroup and stratified analyses revealed a potential influence of smoking status and aspirin use on the association between CRP levels and colorectal adenoma risk. The results of the study may have practical value for clinicians screening for colorectal cancer.
Publish Date	2017-03-13 19:06
Citation	Godos J, Biondi A, Galvano F, Basile F, Sciacca S, Giovannucci EL, Grosso G. Markers of systemic inflammation and colorectal adenoma risk: Meta-analysis of observational studies. World J Gastroenterol 2017; 23(10): 1909-1919
URL	http://www.wjgnet.com/1007-9327/full/v23/i10/1909.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i10.1909

Full Article (PDF)	WJG-23-1909.pdf
Full Article (Word)	WJG-23-1909.doc
Manuscript File	31854-Review.docx
Answering Reviewers	31854-Answering reviewers.pdf
Audio Core Tip	31854-Audio core tip.mp3
Biostatistics Review Certificate	31854-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	31854-Conflict-of-interest statement.pdf
Copyright License Agreement	31854-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	31854-Language certificate.pdf
Supplementary Material	Supplementary_Material_20161211183125.docx
Peer-review Report	31854-Peer-review(s).pdf
Scientific Misconduct Check	31854-Scientific misconduct check.pdf
Scientific Editor Work List	31854-Scientific editor work list.pdf