Publication Name	World Journal of Gastroenterology
Manuscript ID	32199
Country	Brazil

Received	2016-12-28 10:56
Peer-Review Started	2016-12-29 14:08
To Make the First Decision	2017-01-19 10:37
Return for Revision	2017-01-23 08:21
Revised	2017-02-03 00:51
Second Decision	2017-03-01 11:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-03-02 17:02
Articles in Press	2017-03-02 17:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-03-15 16:10
Publish the Manuscript Online	2017-03-28 10:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Diet and microbiota in inflammatory bowel disease: The gut in disharmony
Manuscript Source	Invited Manuscript
All Author List	Davy CM Rapozo, Claudio Bernardazzi and Heitor Siffert Pereira de Souza
Funding Agency and Grant Number
Corresponding Author	Heitor Siffert Pereira de Souza, MD, PhD, Serviço de Gastroenterologia e Laboratório Multidisciplinar de Pesquisa, Departamento de Clínica Médica, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, RJ 21941-913, Brazil. heitor.souza@gmail.com
Key Words	Diet; Microbiota; Epigenetics; Crohn’s disease; Ulcerative colitis
Core Tip	The gut microbiota has a recognized role in immunity, and changes in its composition, or dysbiosis, may be the basis for the worldwide increased incidence of inflammatory bowel disease (IBD). Dietary constituents have been shown to affect the immune response and the inflammatory status, in great part mediated through the modulation of the microbiota. Environmental compounds, including nutrients, can induce alterations in the epigenome interface, resulting in long lasting phenotypic or even tissue structure and function modifications. Unravelling the complex molecular basis of the epigenetic, genetic and environmental interactions underlying IBD pathogenesis will have implications for the development of novel therapies.
Publish Date	2017-03-28 10:34
Citation	Rapozo DCM, Bernardazzi C, de Souza HSP. Diet and microbiota in inflammatory bowel disease: The gut in disharmony. World J Gastroenterol 2017; 23(12): 2124-2140
URL	http://www.wjgnet.com/1007-9327/full/v23/i12/2124.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i12.2124

Full Article (PDF)	WJG-23-2124.pdf
Full Article (Word)	WJG-23-2124.doc
Manuscript File	32199-Review.docx
Answering Reviewers	32199-Answering reviewers.pdf
Audio Core Tip	32199-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	32199-Conflict-of-interest statement.pdf
Copyright License Agreement	32199-Copyright assignement.pdf
Non-Native Speakers of English Editing Certificate	32199-Language certificate.pdf
Peer-review Report	32199-Peer-review(s).pdf
Scientific Misconduct Check	32199-Scientific misconduct check.pdf
Scientific Editor Work List	32199-Scientific editor work list.pdf