Publication Name	World Journal of Gastroenterology
Manuscript ID	32289
Country	Canada

Received	2016-12-30 08:33
Peer-Review Started	2017-01-03 09:35
To Make the First Decision	2017-01-19 13:32
Return for Revision	2017-01-19 22:57
Revised	2017-01-24 00:35
Second Decision	2017-03-09 17:55
Accepted by Journal Editor-in-Chief	2017-03-12 05:43
Accepted by Executive Editor-in-Chief	2017-03-20 15:19
Articles in Press	2017-03-20 15:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-04-11 20:48
Publish the Manuscript Online	2017-04-20 15:58

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Dietary compliance in celiac disease
Manuscript Source	Invited Manuscript
All Author List	Hugh James Freeman
Funding Agency and Grant Number
Corresponding Author	Dr. Hugh James Freeman, Professor, Department of Medicine (Gastroenterology), University of British Columbia, 2211 Wesbrook Mall, Vancouver, BC V6T 1Z4, Canada. hugfree@shaw.cac
Key Words	Gluten-free diet; Compliance; Dietary recall; Celiac disease; Fecal immunoreactive peptides; Tissue transglutaminase antibodies
Core Tip	Celiac disease is an immune-mediated disorder that improves with a strict gluten-free diet. Dietary compliance is essential for symptom resolution and reduction of the risk of long-term complications, including malignancy. Recent evidence suggests that resolution of symptoms and normalization of serological antibody markers on a gluten-free diet occurs, but mucosal inflammatory changes may persist, a critical risk factor for long-term complications. Several recent biopsy studies have documented that the small in­testinal mucosa in adult celiac disease may completely normalize within months, but most require up to 2 years or more to demonstrate mucosal recovery and healing. Histopathological rates of resolution on a gluten-free diet appear to be time-dependent, sex-dependent with higher rates in females, and age-dependent, with lower rates in the very elderly.
Publish Date	2017-04-20 15:58
Citation	Freeman HJ. Dietary compliance in celiac disease. World J Gastroenterol 2017; 23(15): 2635-2639
URL	http://www.wjgnet.com/1007-9327/full/v23/i15/2635.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i15.2635

Full Article (PDF)	WJG-23-2635.pdf
Full Article (Word)	WJG-23-2635.doc
Manuscript File	32289-Review.docx
Answering Reviewers	32289-Answering reviewers.pdf
Audio Core Tip	32289-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	32289-Conflict-of-interest statement.pdf
Copyright License Agreement	32289-Copyright assignment.pdf
Peer-review Report	32289-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	32289-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	32289-Scientific misconduct check.pdf
Scientific Editor Work List	32289-Scientific editor work list.pdf