Publication Name	World Journal of Transplantation
Manuscript ID	32710
Country	Mexico

Received	2017-01-20 09:46
Peer-Review Started	2017-01-20 17:15
To Make the First Decision	2017-04-14 10:28
Return for Revision	2017-04-19 14:32
Revised	2017-04-27 05:45
Second Decision	2017-05-09 11:37
Accepted by Journal Editor-in-Chief	2017-05-09 17:36
Accepted by Company Editor-in-Chief	2017-05-15 05:44
Articles in Press	2017-05-15 05:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-06-06 02:20
Publish the Manuscript Online	2017-06-23 03:40

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Neurosciences
Manuscript Type	Review
Article Title	Historical perspective of cell transplantation in Parkinson’s disease
Manuscript Source	Invited Manuscript
All Author List	Alejandra Boronat-García, Magdalena Guerra-Crespo and René Drucker-Colín
Funding Agency and Grant Number	Funding Agency Grant Number DGAPA-PAPIIT IN207116 CONACyT 179927
Corresponding Author	René Drucker-Colín, PhD, Departamento de Neuropatología Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Circuito Exterior s/n, Ciudad Universitaria, 04910 Ciudad de México, México. drucker@unam.mx
Key Words	Parkinson’s disease; Cell replacement; Animal models; Nigrostriatal pathway; Striatum; Dopaminergic loss
Core Tip	The first studies on cell transplantation for Parkinson’s disease were published during the early 80s. Since then, it has been shown that different cell types induce functional benefits but with high variability among subjects. Here, we first provide a general overview of the field during its early years. Then, we discuss some factors associated with the functionality of the graft based on the latest findings, and highlight the importance of understanding basic aspects (e.g., factors influencing graft integration) which ultimately could contribute to reducing the variability of the functional outcome-an important requirement for its application in the clinic.
Publish Date	2017-06-23 03:40
Citation	Boronat-García A, Guerra-Crespo M, Drucker-Colín R. Historical perspective of cell transplantation in Parkinson’s disease. World J Transplant 2017; 7(3): 179-192
URL	http://www.wjgnet.com/2220-3230/full/v7/i3/179.htm
DOI	http://dx.doi.org/10.5500/wjt.v7.i3.179

Full Article (PDF)	WJT-7-179.pdf
Full Article (Word)	WJT-7-179.doc
Manuscript File	32710-Review.doc
Answering Reviewers	32710-Answering reviewers.pdf
Audio Core Tip	32710-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	32710-Conflict-of-interest statement.pdf
Copyright License Agreement	32710-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	32710-Grant application form(s).pdf
Peer-review Report	32710-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	32710-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	32710-Scientific misconduct check.pdf
Scientific Editor Work List	32710-Scientific editor work list.pdf