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Articles Published Processes
6/20/2017 12:12:52 PM | Browse: 806 | Download: 1278
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Received |
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2017-01-30 12:15 |
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Peer-Review Started |
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2017-02-01 20:45 |
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To Make the First Decision |
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2017-03-16 13:43 |
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Return for Revision |
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2017-03-18 19:29 |
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Revised |
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2017-04-08 03:01 |
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Second Decision |
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2017-05-27 01:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-06-01 08:52 |
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Articles in Press |
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2017-06-01 08:52 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-06-13 02:36 |
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Publish the Manuscript Online |
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2017-06-20 12:12 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Basic Study |
| Article Title |
Relevance of proteolysis and proteasome activation in fatty liver graft preservation: An Institut Georges Lopez-1 vs University of Wisconsin appraisal
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mohamed Amine Zaouali, Arnau Panisello-Roselló, Alexandre Lopez, Carlos Castro Benítez, Emma Folch-Puy, Agustín García-Gil, Teresa Carbonell, René Adam and Joan Roselló-Catafau |
| Funding Agency and Grant Number |
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| Corresponding Author |
Joan Roselló-Catafau, Experimental Hepatic Ischemia-Reperfusion Unit, Institut d’Investigacions Biomèdiques de Barcelona, Spanish National Research Council, C/Rosselló 161, 7th floor, 08036 Barcelona, Spain. joan.rosello@iibb.csic.es |
| Key Words |
Liver proteolysis; Proteasome activation; Fatty liver preservation; Institut Georges Lopez-1; University of Wisconsin; High mobility group box 1; Cold ischemia reperfusion injury |
| Core Tip |
Although several reports have confirmed that proteolytic activity during cold storage determines graft outcome after transplantation, the effect of preservation solution on steatotic liver graft proteolysis and on the activation of ATP-dependent proteasome during cold ischemia injury has not been fully investigated. Here, we compared the effect of two preservation solutions Institut Georges Lopez-1(IGL-1) and University of Wisconsin on liver proteolysis and ubiquitin-proteasome activation when steatotic liver grafts were subjected to cold storage. We provide evidence for a protective role of proteasome and proteolysis inhibition using IGL-1 during steatotic liver graft preservation. |
| Publish Date |
2017-06-20 12:12 |
| Citation |
Zaouali MA, Panisello-Roselló A, Lopez A, Castro Benítez C, Folch-Puy E, García-Gil A, Carbonell T, Adam R, Roselló-Catafau J. Relevance of proteolysis and proteasome activation in fatty liver graft preservation: An Institut Georges Lopez-1 vs University of Wisconsin appraisal. World J Gastroenterol 2017; 23(23): 4211-4221 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i23/4211.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i23.4211 |
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