Publication Name	World Journal of Otorhinolaryngology
Manuscript ID	3304
Country	Japan

Received	2013-04-22 08:26
Peer-Review Started	2013-04-22 13:59
To Make the First Decision	2013-05-23 17:19
Return for Revision	2013-05-24 10:35
Revised	2013-06-14 21:34
Second Decision	2013-07-24 13:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-07-25 03:59
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-08-23 12:04
Publish the Manuscript Online	2013-09-06 21:03

ISSN	2218-6247 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Otorhinolaryngology
Manuscript Type	Frontier
Article Title	Cause of idiopathic sudden sensorineural hearing loss: The stress response theory
Manuscript Source	Invited Manuscript
All Author List	Masatsugu Masuda and Jin Kanzaki
Funding Agency and Grant Number	Funding Agency Grant Number Ministry of Health, Labor and Welfare Grant-in-Aid for Young Scientists
Corresponding Author	Masatsugu Masuda, MD, PhD, Department of Otolaryngology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-8611, Japan. masoeur13@mac.com
Key Words	Cause; Idiopathic sudden sensorineural hearing loss; Lateral wall; Nuclear factor κ-light-chain-enhancer of activated B cells; Stress
Core Tip	The present review focuses on the following four points. First, it summarizes etiologies proposed in the last decade to confirm what we know about the cause of idiopathic sudden sensorineural hearing loss (ISHL). Second, it reviews how systemic stressors affect the human body and the cochlea. Third, it reviews the characteristics of the lateral wall that show unique responses to systemic stressors. Finally, it reviews a relatively new concept about the cause of ISHL, the stress response theory, which integrates our knowledge of the cause of ISHL.
Publish Date	2013-09-06 21:03
Citation	Masuda M, Kanzaki J. Cause of idiopathic sudden sensorineural hearing loss: The stress response theory. World J Otorhinolaryngol 2013; 3(3): 42-57
URL	http://www.wjgnet.com/2218-6247/full/v3/i3/42.htm
DOI	http://dx.doi.org/10.5319/wjo.v3.i3.42

Full Article (PDF)	WJO-3-42.pdf
Manuscript File	3304-Review.docx
Answering Reviewers	3304-Answering reviewers.pdf
Copyright License Agreement	3304-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	3304-Language certificate.pdf
Peer-review Report	3304-Peer reviews.pdf
Scientific Editor Work List	3304-Scientific editor work list.doc