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Articles Published Processes
6/14/2017 9:25:57 AM | Browse: 1204 | Download: 2278
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Received |
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2017-02-04 15:02 |
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Peer-Review Started |
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2017-02-05 22:16 |
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To Make the First Decision |
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2017-02-23 10:29 |
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Return for Revision |
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2017-03-13 09:59 |
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Revised |
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2017-03-28 03:51 |
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Second Decision |
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2017-05-04 17:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-05-09 17:11 |
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Articles in Press |
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2017-05-09 17:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-06-06 06:57 |
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Publish the Manuscript Online |
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2017-06-14 09:25 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Case Control Study |
| Article Title |
Systemic interleukin-9 in inflammatory bowel disease: Association with mucosal healing in ulcerative colitis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Malgorzata Matusiewicz, Katarzyna Neubauer, Iwona Bednarz-Misa, Sabina Gorska and Malgorzata Krzystek-Korpacka |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Science Center |
DEC-2011/01/D/NZ5/02835 |
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| Corresponding Author |
Malgorzata Krzystek-Korpacka, PhD, DSc (Med), Department of Medical Biochemistry, Wroclaw Medical University, ul. Chalubinskiego 10, 50-368 Wroclaw, Poland. malgorzata.krzystek-korpacka@umed.wroc.pl |
| Key Words |
Interleukin 9; Mucosal healing; Biomarker; Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Cachexia; Anemia |
| Core Tip |
Based on a large cohort of patients, our results confirm elevation of IL9 in inflammatory bowel disease (IBD). Additionally, the data demonstrate associations between IL9 and both anemia and wasting syndromes accompanying IBD. Importantly, they show that an elevation in systemic IL9 in ulcerative colitis (UC) corresponds to mucosal inflammation, with IL9 displaying a high level of accuracy as a negative marker of mucosal healing. Also, our results demonstrate IL9 to be more tightly associated with proinflammatory and Th1 cytokines in UC and with angiogenic and Th2 cytokines in Crohn’s disease. |
| Publish Date |
2017-06-14 09:25 |
| Citation |
Matusiewicz M, Neubauer K, Bednarz-Misa I, Gorska S, Krzystek-Korpacka M. Systemic interleukin-9 in inflammatory bowel disease: Association with mucosal healing in ulcerative colitis. World J Gastroenterol 2017; 23(22): 4039-4046 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i22/4039.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i22.4039 |
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