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6/14/2017 9:25:57 AM | Browse: 482 | Download: 677
Publication Name World Journal of Gastroenterology
Manuscript ID 33076
Country/Territory Poland
Received
2017-02-04 15:02
Peer-Review Started
2017-02-05 22:16
To Make the First Decision
2017-02-23 10:29
Return for Revision
2017-03-13 09:59
Revised
2017-03-28 03:51
Second Decision
2017-05-04 17:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-05-09 17:11
Articles in Press
2017-05-09 17:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-06-06 06:57
Publish the Manuscript Online
2017-06-14 09:25
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Case Control Study
Article Title Systemic interleukin-9 in inflammatory bowel disease: Association with mucosal healing in ulcerative colitis
Manuscript Source Invited Manuscript
All Author List Malgorzata Matusiewicz, Katarzyna Neubauer, Iwona Bednarz-Misa, Sabina Gorska and Malgorzata Krzystek-Korpacka
Funding Agency and Grant Number
Funding Agency Grant Number
National Science Center DEC-2011/01/D/NZ5/02835
Corresponding author Malgorzata Krzystek-Korpacka, PhD, DSc (Med), Department of Medical Biochemistry, Wroclaw Medical University, ul. Chalubinskiego 10, 50-368 Wroclaw, Poland. malgorzata.krzystek-korpacka@umed.wroc.pl
Keywords Interleukin 9; Mucosal healing; Biomarker; Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Cachexia; Anemia
Core Tip Based on a large cohort of patients, our results confirm elevation of IL9 in inflammatory bowel disease (IBD). Additionally, the data demonstrate associations between IL9 and both anemia and wasting syndromes accompanying IBD. Importantly, they show that an elevation in systemic IL9 in ulcerative colitis (UC) corresponds to mucosal inflammation, with IL9 displaying a high level of accuracy as a negative marker of mucosal healing. Also, our results demonstrate IL9 to be more tightly associated with proinflammatory and Th1 cytokines in UC and with angiogenic and Th2 cytokines in Crohn’s disease.
Publish Date 2017-06-14 09:25
Citation Matusiewicz M, Neubauer K, Bednarz-Misa I, Gorska S, Krzystek-Korpacka M. Systemic interleukin-9 in inflammatory bowel disease: Association with mucosal healing in ulcerative colitis. World J Gastroenterol 2017; 23(22): 4039-4046
Url http://www.wjgnet.com/1007-9327/full/v23/i22/4039.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i22.4039
Full Article (PDF) WJG-23-4039.pdf
Full Article (Word) WJG-23-4039.doc
Manuscript File 33076-Review.docx
Answering Reviewers 33076-Answering reviewers.pdf
Audio Core Tip 33076-Audio core tip.mp3
Biostatistics Review Certificate 33076-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 33076-Conflict-of-interest statement.pdf
Copyright License Agreement 33076-Copyright assignment.pdf
Data Sharing Statement 33076-Data sharing statement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 33076-Grant application form.pdf
Signed Informed Consent Form(s) or Document(s) 33076-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 33076-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 33076-Language certificate.pdf
Scientific Research Process 33076-Scientific research process.pdf
Peer-review Report 33076-Peer-review(s).pdf
Scientific Misconduct Check 33076-Scientific misconduct check.pdf
Scientific Editor Work List 33076-Scientific editor work list.pdf