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7/28/2017 8:16:18 AM | Browse: 348 | Download: 663
Publication Name World Journal of Gastroenterology
Manuscript ID 33102
Country/Territory Italy
2017-02-06 16:33
Peer-Review Started
2017-02-09 09:10
To Make the First Decision
2017-04-21 10:03
Return for Revision
2017-04-27 10:56
2017-05-04 19:00
Second Decision
2017-07-06 07:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-07-12 05:58
Articles in Press
2017-07-12 05:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-07-19 02:35
Publish the Manuscript Online
2017-07-28 08:16
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Clinical significance of glycemic parameters on venous thromboembolism risk prediction in gastrointestinal cancer
Manuscript Source Invited Manuscript
All Author List Fiorella Guadagni, Silvia Riondino, Vincenzo Formica, Girolamo Del Monte, Anna Maria Morelli, Jessica Lucchetti, Antonella Spila, Roberta D'Alessandro, David Della-Morte, Patrizia Ferroni and Mario Roselli
Funding Agency and Grant Number
Corresponding author Patrizia Ferroni, MD, PhD, San Raffaele Roma Open University, Via di Val Cannuta 247, Rome 00166, Italy. patrizia.ferroni@sanraffaele.it
Keywords Gastrointestinal cancer; type 2 diabetes; venous thromboembolism; chemotherapy; insulin resistance
Core Tip The predictive value of pre-treatment fasting blood glucose, insulin, HbA1c and homeostasis model of risk assessment (HOMA) was investigated in a cohort of gastrointestinal (GI) cancer patients. Despite all investigated metabolic markers were associated with an increased VTE risk during chemotherapy at ROC analysis, only elevated HOMA index (HR = 4.13) or fasting blood glucose (HR = 3.56) had an independent predictive value in survival analyses after adjustment for major confounders. These results suggest that glycemic metabolic markers, mainly HOMA index, should be carefully monitored in chemotherapy-treated GI cancer patients, as they could help to identify patients who might benefit from thromboprophylaxis.
Publish Date 2017-07-28 08:16
Citation Guadagni F, Riondino S, Formica V, Del Monte G, Morelli AM, Lucchetti J, Spila A, D’Alessandro R, Della-Morte D, Ferroni P, Roselli M. Clinical significance of glycemic parameters on venous thromboembolism risk prediction in gastrointestinal cancer. World J Gastroenterol 2017; 23(28): 5187-5195
Url http://www.wjgnet.com/1007-9327/full/v23/i28/5187.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i28.5187
Full Article (PDF) WJG-23-5187.pdf
Full Article (Word) WJG-23-5187.doc
Manuscript File 33102-Review.docx
Answering Reviewers 33102-Answering reviewers.pdf
Audio Core Tip 33102-Audio core tip.m4a
Biostatistics Review Certificate 33102-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 33102-Conflict-of-interest statement.pdf
Copyright License Agreement 33102-Copyright assignment.pdf
Data Sharing Statement 33102-Data sharing statement.pdf
Signed Informed Consent Form(s) or Document(s) 33102-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 33102-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 33102_33102-Language certificate.docx
Scientific Research Process 33102-Scientific research process.pdf
Supplementary Material 33102-Supplementary material.pdf
Peer-review Report 33102-Peer-review(s).pdf
Scientific Misconduct Check 33102-Scientific misconduct check.pdf
Scientific Editor Work List 33102-Scientific editor work list.pdf