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Articles Published Processes
7/28/2017 8:16:18 AM | Browse: 1316 | Download: 3552
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Received |
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2017-02-06 16:33 |
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Peer-Review Started |
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2017-02-09 09:10 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2017-04-27 10:56 |
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Revised |
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2017-05-04 19:00 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2017-07-06 07:14 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2017-07-12 05:58 |
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Articles in Press |
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2017-07-12 05:58 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-07-19 02:35 |
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Publish the Manuscript Online |
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2017-07-28 08:16 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Clinical significance of glycemic parameters on venous thromboembolism risk prediction in gastrointestinal cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Fiorella Guadagni, Silvia Riondino, Vincenzo Formica, Girolamo Del Monte, Anna Maria Morelli, Jessica Lucchetti, Antonella Spila, Roberta D'Alessandro, David Della-Morte, Patrizia Ferroni and Mario Roselli |
| Funding Agency and Grant Number |
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| Corresponding Author |
Patrizia Ferroni, MD, PhD, San Raffaele Roma Open University, Via di Val Cannuta 247, Rome 00166, Italy. patrizia.ferroni@sanraffaele.it |
| Key Words |
Gastrointestinal cancer; type 2 diabetes; venous thromboembolism; chemotherapy; insulin resistance |
| Core Tip |
The predictive value of pre-treatment fasting blood glucose, insulin, HbA1c and homeostasis model of risk assessment (HOMA) was investigated in a cohort of gastrointestinal (GI) cancer patients. Despite all investigated metabolic markers were associated with an increased VTE risk during chemotherapy at ROC analysis, only elevated HOMA index (HR = 4.13) or fasting blood glucose (HR = 3.56) had an independent predictive value in survival analyses after adjustment for major confounders. These results suggest that glycemic metabolic markers, mainly HOMA index, should be carefully monitored in chemotherapy-treated GI cancer patients, as they could help to identify patients who might benefit from thromboprophylaxis. |
| Publish Date |
2017-07-28 08:16 |
| Citation |
Guadagni F, Riondino S, Formica V, Del Monte G, Morelli AM, Lucchetti J, Spila A, D’Alessandro R, Della-Morte D, Ferroni P, Roselli M. Clinical significance of glycemic parameters on venous thromboembolism risk prediction in gastrointestinal cancer. World J Gastroenterol 2017; 23(28): 5187-5195 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i28/5187.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i28.5187 |
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