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Articles Published Processes
6/14/2017 9:25:57 AM | Browse: 1211 | Download: 2123
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Received |
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2017-02-08 10:33 |
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Peer-Review Started |
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2017-02-08 15:01 |
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To Make the First Decision |
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2017-02-23 09:56 |
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Return for Revision |
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2017-02-27 16:44 |
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Revised |
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2017-03-10 11:37 |
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Second Decision |
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2017-04-27 17:24 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-05-04 18:23 |
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Articles in Press |
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2017-05-04 18:23 |
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Publication Fee Transferred |
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2017-05-09 11:45 |
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Edit the Manuscript by Language Editor |
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2017-05-13 09:34 |
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Typeset the Manuscript |
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2017-06-08 05:34 |
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Publish the Manuscript Online |
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2017-06-14 09:25 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Association of keratin 8/18 variants with non-alcoholic fatty liver disease and insulin resistance in Chinese patients: A case-control study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Rui Li, Xian-Hua Liao, Jun-Zhao Ye, Min-Rui Li, Yan-Qin Wu, Xuan Hu and Bi-Hui Zhong |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81670518 |
| National Natural Science Foundation of China |
81170392 |
| Science and Technology Project of Guangdong Province, China |
2013B021800290 |
| Science and Technology Project of Guangdong Province, China |
2014A020212118 |
| Guangzhou Science Technology and Innovation Commission, China |
201604020155 |
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| Corresponding Author |
Bi-Hui Zhong, MD, PhD, Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan Road II, Guangzhou 510080, Guangdong Province, China. sophiazhong@medmail.com.cn |
| Key Words |
Keratin; Variant; Non-alcoholic fatty liver disease; Insulin resistance; Chinese population |
| Core Tip |
This study presents the first investigation of the association between keratin 8 and 18 (K8/K18) variants and non-alcoholic fatty liver disease (NAFLD) in a Chinese population. We found an increased frequency of variants in NAFLD patients vs controls. We also identified a new amino acid-altering variant of K18. The results demonstrate that keratin variants are overrepresented in Chinese NAFLD patients and might accelerate liver fat storage through insulin resistance. |
| Publish Date |
2017-06-14 09:25 |
| Citation |
Li R, Liao XH, Ye JZ, Li MR, Wu YQ, Hu X, Zhong BH. Association of keratin 8/18 variants with non-alcoholic fatty liver disease and insulin resistance in Chinese patients: a case-control study. World J Gastroenterol 2017; 23(22): 4047-4053 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i22/4047.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i22.4047 |
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