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6/14/2017 9:25:57 AM | Browse: 454 | Download: 449
Publication Name World Journal of Gastroenterology
Manuscript ID 33298
Country/Territory China
Received
2017-02-08 10:33
Peer-Review Started
2017-02-08 15:01
To Make the First Decision
2017-02-23 09:56
Return for Revision
2017-02-27 16:44
Revised
2017-03-10 11:37
Second Decision
2017-04-27 17:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-05-04 18:23
Articles in Press
2017-05-04 18:23
Publication Fee Transferred
2017-05-09 11:45
Edit the Manuscript by Language Editor
2017-05-13 09:34
Typeset the Manuscript
2017-06-08 05:34
Publish the Manuscript Online
2017-06-14 09:25
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Case Control Study
Article Title Association of keratin 8/18 variants with non-alcoholic fatty liver disease and insulin resistance in Chinese patients: A case-control study
Manuscript Source Unsolicited Manuscript
All Author List Rui Li, Xian-Hua Liao, Jun-Zhao Ye, Min-Rui Li, Yan-Qin Wu, Xuan Hu and Bi-Hui Zhong
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81670518
National Natural Science Foundation of China 81170392
Science and Technology Project of Guangdong Province, China 2013B021800290
Science and Technology Project of Guangdong Province, China 2014A020212118
Guangzhou Science Technology and Innovation Commission, China 201604020155
Corresponding author Bi-Hui Zhong, MD, PhD, Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan Road II, Guangzhou 510080, Guangdong Province, China. sophiazhong@medmail.com.cn
Keywords Keratin; Variant; Non-alcoholic fatty liver disease; Insulin resistance; Chinese population
Core Tip This study presents the first investigation of the association between keratin 8 and 18 (K8/K18) variants and non-alcoholic fatty liver disease (NAFLD) in a Chinese population. We found an increased frequency of variants in NAFLD patients vs controls. We also identified a new amino acid-altering variant of K18. The results demonstrate that keratin variants are overrepresented in Chinese NAFLD patients and might accelerate liver fat storage through insulin resistance.
Publish Date 2017-06-14 09:25
Citation Li R, Liao XH, Ye JZ, Li MR, Wu YQ, Hu X, Zhong BH. Association of keratin 8/18 variants with non-alcoholic fatty liver disease and insulin resistance in Chinese patients: a case-control study. World J Gastroenterol 2017; 23(22): 4047-4053
Url http://www.wjgnet.com/1007-9327/full/v23/i22/4047.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i22.4047
Full Article (PDF) WJG-23-4047.pdf
Full Article (Word) WJG-23-4047.doc
Manuscript File 33298-Review.docx
Answering Reviewers 33298-Answering reviewers.pdf
Audio Core Tip 33298-Audio core tip.mp3
Biostatistics Review Certificate 33298-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 33298-Conflict-of-interest statement.pdf
Copyright License Agreement 33298-Copyright assignment.pdf
Data Sharing Statement 33298-Data sharing statement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 33298-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 33298-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 33298-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 33298-Language certificate.pdf
Scientific Research Process 33298-Scientific research process.pdf
Peer-review Report 33298-Peer-review(s).pdf
Scientific Misconduct Check 33298-Scientific misconduct check.pdf
Scientific Editor Work List 33298-Scientific editor work list.pdf