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8/19/2017 11:33:54 AM | Browse: 314 | Download: 417
Publication Name World Journal of Gastroenterology
Manuscript ID 33523
Country/Territory China
2017-02-14 08:39
Peer-Review Started
2017-02-14 17:16
To Make the First Decision
2017-04-07 17:20
Return for Revision
2017-04-07 17:24
2017-05-14 13:48
Second Decision
2017-06-06 00:42
Accepted by Journal Editor-in-Chief
2017-06-08 00:47
Accepted by Company Editor-in-Chief
2017-06-12 08:41
Articles in Press
2017-06-12 08:41
Publication Fee Transferred
2017-06-13 05:01
Edit the Manuscript by Language Editor
2017-06-29 21:13
Typeset the Manuscript
2017-08-14 02:46
Publish the Manuscript Online
2017-08-19 11:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Protective effects of Foeniculum vulgare root bark extract against carbon tetrachloride-induced hepatic fibrosis in mice
Manuscript Source Unsolicited Manuscript
All Author List Cai Zhang, Xing Tian, Ke Zhang, Guo-Yu Li, Hang-Yu Wang and Jin-Hui Wang
Funding Agency and Grant Number
Funding Agency Grant Number
National Key Technology R&D Program 2012BAI30B02
Corresponding author Xing Tian , PhD, School of Pharmacy, Shihezi University, North Road 4, Shihezi 832002, Xinjiang Uygur Autonomous Region, China. tianxing2017@shzu.edu.cn
Keywords Hepatic fibrosis; Foeniculum vulgare root bark; Histopathology; Carbon tetrachloride; TGF-β1
Core Tip Hepatic fibrosis is a wound-healing patho­logical process resulting from chronic hepatic injuries. In the present study, hepatoprotective effects of Foeniculum vulgare root bark (FVRB), a traditional Uyghur medicine, against carbon tetrachloride (CCl4)-induced hepatic fibrosis in mice were investigated. FVRB reduced serum levels of aspartate aminotransferase, alanine aminotransferase, triglyceride, hexadecenoic acid and laminin. Furthermore, FVRB inhibited CCl4-induced TGF-β1, MMP-9, TIMP-1 expression and histopathological changes. Our study indicated that the protective effects of FVRB are through inhibiting lipid peroxidation and collagen formation in liver tissue of liver fibrosis mice.
Publish Date 2017-08-19 11:33
Citation Zhang C, Tian X, Zhang K, Li GY, Wang HY, Wang JH. Protective effects of Foeniculum vulgare root bark extract against carbon tetrachloride-induced hepatic fibrosis in mice. World J Gastroenterol 2017; 23(31): 5722-5731
Url http://www.wjgnet.com/1007-9327/full/v23/i31/5722.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i31.5722
Full Article (PDF) WJG-23-5722.pdf
Full Article (Word) WJG-23-5722.doc
Manuscript File 33523-Review.docx
Answering Reviewers 33523-Answering reviewers.pdf
Audio Core Tip 33523-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 33523-Conflict-of-interest statement.pdf
Copyright License Agreement 33523-Copyright assignment.pdf
Data Sharing Statement 33523-Data sharing statement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 33523-Grant application form(s).pdf
Scientific Research Process 33523-Scientific research process.pdf
Peer-review Report 33523-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 33523-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 33523-Scientific misconduct check.pdf
Scientific Editor Work List 33523-Scientific editor work list.pdf