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7/7/2017 11:41:16 AM | Browse: 1001 | Download: 1729
Publication Name World Journal of Gastroenterology
Manuscript ID 33550
Country China
Received
2017-02-16 09:14
Peer-Review Started
2017-02-16 21:44
To Make the First Decision
2017-04-07 17:20
Return for Revision
2017-04-07 17:25
Revised
2017-04-10 17:01
Second Decision
2017-05-18 03:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-05-19 08:00
Articles in Press
2017-05-19 08:00
Publication Fee Transferred
2017-05-27 07:33
Edit the Manuscript by Language Editor
2017-06-01 10:39
Typeset the Manuscript
2017-06-24 09:01
Publish the Manuscript Online
2017-07-07 11:41
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Partners of patients with ulcerative colitis exhibit a biologically relevant dysbiosis in fecal microbial metacommunities
Manuscript Source Unsolicited Manuscript
All Author List Guang-Lan Chen, Ye Zhang, Wang-Yue Wang, Xue-Liang Ji, Fei Meng, Pei-Song Xu, Ning-Min Yang, Fu-Qiang Ye and Xiao-Chen Bo
Funding Agency and Grant Number
Funding Agency Grant Number
Lishui Science and Technology Bureau Research Fund 2013JYZB43
Medical and Health Science and Technology Plan Project of Zhejiang Province 2015KYB371
Corresponding Author Dr. Xiao-Chen Bo, Department of Radiation Toxicology and Oncology, Beijing Institute of Radiation Medicine, People’s Republic of China, Beijing 100089, China. boxc@bmi.ac.cn
Key Words Ulcerative colitis; Patients; Healthy partner; Fecal microbial communities; Microbiota dysbiosis
Core Tip To identify the influence on the gut microbial community between ulcerative colitis (UC) patients and their healthy partners, we investigated the gut bacterial community using 16S rRNA amplicon sequencing. The results showed that fecal microbial communities were more similar in UC patients, which had a lower relative abundance of Firmicutes bacteria. Microbiota dysbiosis was also founded in healthy partners. The pathways involved in lipid and nucleotide metabolism were more abundant in the UC patients. The membrane transport and metabolism of cofactors and vitamins pathways were significantly enriched in the healthy partners. Microbial composition might be affected in healthy partners cohabiting with UC patients.
Publish Date 2017-07-07 11:41
Citation Chen GL, Zhang Y, Wang WY, Ji XL, Meng F, Xu PS, Yang NM, Bo XC. Partners of patients with ulcerative colitis exhibit a biologically relevant dysbiosis in fecal microbial metacommunities. World J Gastroenterol 2017; 23(25): 4624-4631
URL http://www.wjgnet.com/1007-9327/full/v23/i25/4624.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i25.4624
Full Article (PDF) WJG-23-4624.pdf
Full Article (Word) WJG-23-4624.doc
Manuscript File 33550-Review.docx
Answering Reviewers 33550-Answering reviewers.pdf
Audio Core Tip 33550-Audio core tip.mp3
Biostatistics Review Certificate 33550-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 33550-Conflict-of-interest statement.pdf
Copyright License Agreement 33550-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 33550-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 33550-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 33550-Language certificate.pdf
Peer-review Report 33550-Peer-review(s).pdf
Scientific Misconduct Check 33550-Scientific misconduct check.pdf
Scientific Editor Work List 33550-Scientific editor work list.pdf