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Articles Published Processes
7/7/2017 11:41:16 AM | Browse: 1115 | Download: 2081
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Received |
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2017-02-16 09:14 |
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Peer-Review Started |
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2017-02-16 21:44 |
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To Make the First Decision |
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2017-04-07 17:20 |
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Return for Revision |
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2017-04-07 17:25 |
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Revised |
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2017-04-10 17:01 |
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Second Decision |
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2017-05-18 03:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-05-19 08:00 |
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Articles in Press |
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2017-05-19 08:00 |
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Publication Fee Transferred |
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2017-05-27 07:33 |
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Edit the Manuscript by Language Editor |
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2017-06-01 10:39 |
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Typeset the Manuscript |
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2017-06-24 09:01 |
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Publish the Manuscript Online |
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2017-07-07 11:41 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Observational Study |
Article Title |
Partners of patients with ulcerative colitis exhibit a biologically relevant dysbiosis in fecal microbial metacommunities
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Guang-Lan Chen, Ye Zhang, Wang-Yue Wang, Xue-Liang Ji, Fei Meng, Pei-Song Xu, Ning-Min Yang, Fu-Qiang Ye and Xiao-Chen Bo |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Lishui Science and Technology Bureau Research Fund |
2013JYZB43 |
Medical and Health Science and Technology Plan Project of Zhejiang Province |
2015KYB371 |
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Corresponding Author |
Dr. Xiao-Chen Bo, Department of Radiation Toxicology and Oncology, Beijing Institute of Radiation Medicine, People’s Republic of China, Beijing 100089, China. boxc@bmi.ac.cn |
Key Words |
Ulcerative colitis; Patients; Healthy partner; Fecal microbial communities; Microbiota dysbiosis |
Core Tip |
To identify the influence on the gut microbial community between ulcerative colitis (UC) patients and their healthy partners, we investigated the gut bacterial community using 16S rRNA amplicon sequencing. The results showed that fecal microbial communities were more similar in UC patients, which had a lower relative abundance of Firmicutes bacteria. Microbiota dysbiosis was also founded in healthy partners. The pathways involved in lipid and nucleotide metabolism were more abundant in the UC patients. The membrane transport and metabolism of cofactors and vitamins pathways were significantly enriched in the healthy partners. Microbial composition might be affected in healthy partners cohabiting with UC patients. |
Publish Date |
2017-07-07 11:41 |
Citation |
Chen GL, Zhang Y, Wang WY, Ji XL, Meng F, Xu PS, Yang NM, Bo XC. Partners of patients with ulcerative colitis exhibit a biologically relevant dysbiosis in fecal microbial metacommunities. World J Gastroenterol 2017; 23(25): 4624-4631 |
URL |
http://www.wjgnet.com/1007-9327/full/v23/i25/4624.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v23.i25.4624 |
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