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Articles Published Processes
7/12/2017 6:45:23 AM | Browse: 1559 | Download: 3578
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Received |
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2017-02-21 10:29 |
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Peer-Review Started |
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2017-02-22 17:35 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2017-04-06 12:15 |
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Revised |
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2017-04-30 22:31 |
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Publication Fee Transferred |
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2017-06-20 03:42 |
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Second Decision by Editor |
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2017-06-16 12:17 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2017-06-19 08:41 |
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Articles in Press |
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2017-06-19 08:41 |
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Edit the Manuscript by Language Editor |
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2017-06-24 20:59 |
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Typeset the Manuscript |
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2017-07-04 11:34 |
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Publish the Manuscript Online |
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2017-07-12 06:45 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Jianpi Qingchang decoction regulates intestinal motility of dextran sulfate sodium-induced colitis through reducing autophagy of interstitial cells of Cajal
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan-Cheng Dai, Lie Zheng, Ya-Li Zhang, Xuan Chen, De-Liang Chen, Li-Juan Wang and Zhi-Peng Tang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81403355 |
| National Natural Science Foundation of China |
81573892 |
| Project of 3-Year Action Plan for Shanghai Municipal Chinese Medicine Development |
ZY3-RCPY-2-2001 |
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| Corresponding Author |
Zhi-Peng Tang, MD, PhD, Professor, Director, Institute of Digestive Diseases, Shanghai University of Traditional Chinese Medicine, 725 Wanping Road, Shanghai 200032, China. zhipengtang@sohu.com |
| Key Words |
intestinal motility; Interstitial cells of Cajal; autophagy; ulcerative colitis; Jianpi Qingchang decoction |
| Core Tip |
Interstitial cells of Cajal (ICC) lead to a variety of changes in the physiological properties of the neurons in the related circuitry, which then affects gastrointestinal motility. Therefore, ICC have been accepted as a therapeutic target for gastrointestinal motility disorders. It is demonstrated in the current study that Jianpi Qingchang decoction can regulate the intestinal motility of dextran sulfate sodium-induced colitis in mice through suppressing intestinal inflammatory cascade reaction, reducing autophagy of ICC, and regulating the network path of ICC/smooth muscle cells. |
| Publish Date |
2017-07-12 06:45 |
| Citation |
Dai YC, Zheng L, Zhang YL, Chen X, Chen DL, Wang LJ, Tang ZP. Jianpi Qingchang decoction regulates intestinal motility of dextran sulfate sodium-induced colitis through reducing autophagy of interstitial cells of Cajal. World J Gastroenterol 2017; 23(26): 4724-4734 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i26/4724.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i26.4724 |
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