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9/11/2017 1:10:54 AM | Browse: 1321 | Download: 1170
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 33683
Country/Territory United States
Received
2017-02-25 11:53
Peer-Review Started
2017-02-27 08:17
To Make the First Decision
2017-05-23 00:52
Return for Revision
2017-06-12 04:03
Revised
2017-06-27 00:31
Second Decision
2017-07-28 05:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-08-04 06:17
Articles in Press
2017-08-04 06:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-08-31 09:07
Publish the Manuscript Online
2017-09-11 01:10
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Epigenetics of gastroenteropancreatic neuroendocrine tumors: A clinicopathologic perspective
Manuscript Source Invited Manuscript
All Author List Brendan M Finnerty, Katherine D Gray, Maureen D Moore, Rasa Zarnegar and Thomas J Fahey III
Funding Agency and Grant Number
Corresponding Author Brendan M Finnerty, MD, Department of Surgery, New York Presbyterian Hospital, Weill Cornell Medicine, York Ave, Suite A1027, New York, NY 10065, United States. bmf9002@nyp.org
Key Words Epigenetics; Carcinoid; Neuroendocrine; MicroRNA; Methylation; Histone modifications; Chromatin remodeling; LncRNA
Core Tip Herein, we describe a review of the literature addressing known epigenetic changes which are thought to lead to the development of gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Through a variety of scientific works, methylation patterns, chromatin remodeling alterations, and microRNA and long non-coding RNA differential expression profiles have been identified and in many cases correlated with GEP-NET malignancy and clinical outcomes. This overview shows the strong foundation which exists and underlines the importance of future work to evaluate the clinical efficacy of epigenetic modifications as prognostic biomarkers, as well as potential therapeutic targets.
Publish Date 2017-09-11 01:10
Citation Finnerty BM, Gray KD, Moore MD, Zarnegar R, Fahey Ⅲ TJ. Epigenetics of gastroenteropancreatic neuroendocrine tumors: A clinicopathologic perspective. World J Gastrointest Oncol 2017; 9(9): 341-353
URL http://www.wjgnet.com/1948-5204/full/v9/i9/341.htm
DOI http://dx.doi.org/10.4251/wjgo.v9.i9.341
Full Article (PDF) WJGO-9-341.pdf
Full Article (Word) WJGO-9-341.doc
Manuscript File 33683-Review.docx
Answering Reviewers 33683-Answering reviewers.pdf
Audio Core Tip 33683-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 33683-Conflict-of-interest statement.pdf
Copyright License Agreement 33683-Copyright assignment.PDF
Supplementary Material 33683-Supplementary material.pptx
Peer-review Report 33683-Peer-review(s).pdf
Scientific Misconduct Check 33683-Scientific misconduct check.pdf
Scientific Editor Work List 33683-Scientific editor work list.pdf