Category |
Oncology |
Manuscript Type |
Observational Study |
Article Title |
Prophylactic lateral pelvic lymph node dissection in stage Ⅳ low rectal cancer
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Hiroshi Tamura, Yoshifumi Shimada, Hitoshi Kameyama, Ryoma Yagi, Yosuke Tajima, Takuma Okamura, Mae Nakano, Masato Nakano, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Shin-ichi Kosugi, Hitoshi Nogami, Satoshi Maruyama, Yasumasa Takii and Toshifumi Wakai |
Funding Agency and Grant Number |
|
Corresponding Author |
Yoshifumi Shimada, MD, PhD, Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata 951-8510, Japan. shimaday@med.niigata-u.ac.jp |
Key Words |
Prophylactic lateral pelvic lymph node dissection; Stage Ⅳ; Low rectal cancer |
Core Tip |
The clinical significance of prophylactic lateral pelvic lymph node dissection (LPLND) in stage Ⅳ low rectal cancer has not been proven. In this study, we showed two main findings concerning treatment strategy in these patients. First, prophylactic LPLND was not a significant prognostic factor for overall survival and did not contribute local control. Second, R0 resection was an independent prognostic factor for overall survival. These results suggest that prophylactic LPLND is not an important component of surgical treatment in stage Ⅳ low rectal cancer patients. |
Publish Date |
2017-09-25 04:24 |
Citation |
Tamura H, Shimada Y, Kameyama H, Yagi R, Tajima Y, Okamura T, Nakano M, Nakano M, Nagahashi M, Sakata J, Kobayashi T, Kosugi SI, Nogami H, Maruyama S, Takii Y, Wakai T. Prophylactic lateral pelvic lymph node dissection in stage Ⅳ low rectal cancer. World J Clin Oncol 2017; 8(5): 412-419 |
URL |
http://www.wjgnet.com/2218-4333/full/v8/i5/412.htm |
DOI |
http://dx.doi.org/10.5306/wjco.v8.i5.412 |