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Articles Published Processes
12/20/2017 2:49:19 AM | Browse: 774 | Download: 890
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Received |
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2017-03-25 13:23 |
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Peer-Review Started |
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2017-03-29 16:10 |
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To Make the First Decision |
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2017-04-21 09:35 |
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Return for Revision |
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2017-04-24 16:05 |
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Revised |
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2017-05-14 22:38 |
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Second Decision |
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2017-05-27 01:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2017-06-01 07:01 |
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Articles in Press |
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2017-06-01 07:01 |
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Publication Fee Transferred |
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2017-07-06 17:02 |
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Edit the Manuscript by Language Editor |
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2017-09-23 20:57 |
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Typeset the Manuscript |
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2017-12-18 06:14 |
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Publish the Manuscript Online |
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2017-12-20 02:49 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author (s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Nezha Senhaji, Sellama Nadifi, Younes Zaid, Aurora Serrano, Daniel Arturo Leon Rodriguez, Nadia Serbati, Mehdi Karkouri, Wafaa Badre and Javier Martin |
| Funding Agency and Grant Number |
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| Corresponding Author |
Nezha Senhaji, PhD, Laboratory of Genetics and Molecular Pathology, Faculty of Medicine and Pharmacy of Casablanca, University Hassan II.
19, rue Tarik Ibnou Ziad, Faculté de Médecine et de Pharmacie, Casablanca 20100, Morocco. nezha.senhaji05@etude.univcasa.ma |
| Key Words |
HIF1A; NFKB1; NOS2A; Inflammatory bowel disease; Moroccan patients |
| Core Tip |
This is the first study to assess the involvement of oxidative pathway related genes in inflammatory bowel disease (IBD) development and to determine a possible effect of these variants on clinical course. We genotyped 507 subjects grouped in 308 healthy controls and 199 IBD patients for the (TAAA)n_rs12720460 and (CCTTT)n_rs3833912 NOS2A microsatellite repeats, HIF-1A_rs11549467 and NFKB1-94ins/delATTG_rs28362491 polymorphisms. The present study showed that NOS2A_ (CCTTT)n gene variations may influence IBD susceptibility in the Moroccan population. However, our data do not support a role for the NFKB1 and HIF1A polymorphisms in the pathogenesis of IBD. |
| Publish Date |
2017-12-20 02:49 |
| Citation |
Senhaji N, Nadifi S, Zaid Y, Serrano A, Rodriguez DAL, Serbati N, Karkouri M, Badre W, Martín J. Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease. World J Gastroenterol 2017; 23(47): 8300-8307 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i47/8300.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i47.8300 |
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