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12/27/2017 10:31:19 AM | Browse: 834 | Download: 1267
Publication Name World Journal of Hepatology
Manuscript ID 34331
Country Japan
Received
2017-06-19 00:45
Peer-Review Started
2017-06-19 07:25
To Make the First Decision
2017-07-10 00:50
Return for Revision
2017-07-20 07:54
Revised
2017-10-15 13:12
Second Decision
2017-11-14 11:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2017-11-20 06:48
Articles in Press
2017-11-20 06:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-11-29 18:35
Typeset the Manuscript
2017-12-26 01:02
Publish the Manuscript Online
2017-12-27 10:31
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Primary biliary cholangitis metachronously complicated with combined hepatocellular carcinomacholangiocellular carcinoma and hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Ryuta Ide, Akihiko Oshita, Takashi Nishisaka, Hideki Nakahara, Shiomi Aimitsu and Toshiyuki Itamoto
ORCID
Author(s) ORCID Number
Ryuta Ide http://orcid.org/0000-0002-7263-2213
Akihiko Oshita http://orcid.org/0000-0001-8417-7599
Takashi Nishisaka http://orcid.org/0000-0003-1978-4717
Hideki Nakahara http://orcid.org/0000-0003-1629-6259
Shiomi Aimitsu http://orcid.org/0000-0002-1281-0380
Toshiyuki Itamoto http://orcid.org/0000-0002-8353-4782
Funding Agency and Grant Number
Corresponding Author Akihiko Oshita, MD, PhD, Surgeon, Department of Gastroenterological Surgery, Hiroshima Prefectural Hospital, 1-5-54 Ujina-kanda, Minami-ku, Hiroshima 734-8530, Japan. oshita-akihiko@umin.ac.jp
Key Words Primary biliary cholangitis; Combined hepatocellular carcinoma and cholangiocellular carcinoma; Hepatocellular carcinoma
Core Tip Primary biliary cholangitis (PBC) is a progressive cholestatic liver disease characterized by the presence of highly specific antimitochondrial antibodies, portal inflammation and lymphocyte-dominated destruction of the intrahepatic bile ducts, which leads to cirrhosis. While its pathogenesis remains unclear, PBC that shows histological progression to fibrosis carries a high risk of carcinogenesis; the same is true of viral liver diseases. In patients with PBC, the development of hepatocellular carcinoma is rare; the development of combined hepatocellular carcinoma and cholangiocellular carcinoma (cHCC-CCC) is extraordinary. Herein, we report a rare case of PBC metachronously complicated by cHCC-CCC and HCC; which, to the best of our knowledge, has never been reported.
Publish Date 2017-12-27 10:31
Citation Ide R, Oshita A, Nishisaka T, Nakahara H, Aimitsu S, Itamoto T. Primary biliary cholangitis metachronously complicated with combined hepatocellular carcinoma-cholangiocellular carcinoma and hepatocellular carcinoma. World J Hepatol 2017; 9(36): 1378-1384 Available from: URL: http://www.wjgnet.com/1948-5182/full/v9/i36/1378.htm DOI: http://dx.doi.org/10.4254/wjh.v9.i36.1378
URL http://www.wjgnet.com/1948-5182/full/v9/i36/1378.htm
DOI http://dx.doi.org/10.4254/wjh.v9.i36.1378
Full Article (PDF) WJH-9-1378.pdf
Full Article (Word) WJH-9-1378.doc
Manuscript File 34331-Review.docx
Answering Reviewers 34331-Answering reviewers.pdf
Audio Core Tip 34331-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 34331-Conflict-of-interest statement.pdf
Copyright License Agreement 34331-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 34331-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 34331-Language certificate.pdf
Peer-review Report 34331-Peer-review(s).pdf
Scientific Misconduct Check 34331-Scientific misconduct check.pdf
Scientific Editor Work List 34331-Scientific editor work list.pdf