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Articles Published Processes
8/19/2017 11:33:54 AM | Browse: 1054 | Download: 1905
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Received |
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2017-05-04 09:36 |
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Peer-Review Started |
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2017-05-04 21:35 |
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To Make the First Decision |
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2017-06-05 00:59 |
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Return for Revision |
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2017-06-06 09:32 |
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Revised |
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2017-06-10 01:52 |
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Second Decision |
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2017-07-05 23:54 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-07-12 06:24 |
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Articles in Press |
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2017-07-12 06:24 |
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Publication Fee Transferred |
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2017-07-13 10:22 |
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Edit the Manuscript by Language Editor |
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2017-07-29 02:31 |
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Typeset the Manuscript |
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2017-08-13 06:16 |
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Publish the Manuscript Online |
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2017-08-19 11:33 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index and liver stiffness measurement in hepatitis B virus-infected patients with persistently normal alanine aminotransferase
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
You-Wen Tan, Xing-Bei Zhou, Yun Ye, Cong He and Guo-Hong Ge |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
You-Wen Tan, Doctor, Doctor, Department of Hepatosis, the Third Hospital of Zhenjiang Affiliated Jiangsu University, Daijiamen 300, Zhenjiang 212001, Jiangsu Province, China. tyw915@sina.com |
Key Words |
Liver stiffness measurement; Hepatitis B virus; FIB-4; Aspartate aminotransferase-to-platelet ratio index; Normal; Alanine aminotransferase |
Core Tip |
To assess the diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index (APRI), and liver stiffness measurement (LSM) in patients with hepatitis B virus infection who have persistently normal alanine transaminase (PNALT), we enrolled 245 patients with chronic hepatitis B: 95 in PNALT group, 86 in intermittently elevated alanine transaminase (PIALT1) group [alanine transaminase (ALT) within 1-2 × upper limit of normal value (ULN)], and 64 in PIALT2 group (ALT > 2 × ULN). The results showed that APRI and FIB-4 are not the ideal noninvasive hepatic fibrosis markers for PNALT patients. LSM is superior to APRI and FIB-4 in PNALT patients because of the influence of liver inflammation and necrosis. |
Publish Date |
2017-08-19 11:33 |
Citation |
Tan YW, Zhou XB, Ye Y, He C, Ge GH. Diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index and liver stiffness measurement in hepatitis B virus-infected patients with persistently normal alanine aminotransferase. World J Gastroenterol 2017; 23(31): 5746-5754 |
URL |
http://www.wjgnet.com/1007-9327/full/v23/i31/5746.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v23.i31.5746 |
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