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Articles Published Processes
9/14/2017 3:13:08 AM | Browse: 1836 | Download: 2870
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Received |
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2017-06-07 00:27 |
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Peer-Review Started |
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2017-06-08 07:06 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2017-07-17 11:55 |
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Revised |
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2017-07-29 12:28 |
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Publication Fee Transferred |
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2017-08-22 02:48 |
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Second Decision by Editor |
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2017-08-15 07:12 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2017-08-15 15:12 |
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Articles in Press |
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2017-08-15 15:12 |
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Edit the Manuscript by Language Editor |
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2017-08-26 07:36 |
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Typeset the Manuscript |
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2017-09-07 02:41 |
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Publish the Manuscript Online |
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2017-09-14 03:13 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Basic Study |
| Article Title |
Curcumin inhibits hepatitis B virus infection by down-regulating cccDNA-bound histone acetylation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi-Qiang Wei, Yong-Hong Zhang, Chang-Zheng Ke, Hong-Xia Chen, Pan Ren, Yu-Lin He, Pei Hu, De-Qiang Ma, Jie Luo and Zhong-Ji Meng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81541140 |
| Natural Science Foundation of the Hubei Province of China |
2014CFB645 |
| Research and Development Project of the Science and Technology Plan of Hubei Province |
2011BCB030 |
| Foundation for Innovative Research Team of Hubei University of Medicine |
2014CXG05 |
| Key Program for Precision Medicine of Taihe Hospital |
2016JZ05 |
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| Corresponding Author |
Zhong-Ji Meng, MD, Professor, Institute of Biomedical Research, Taihe Hospital, Hubei University of Medicine, South Renmin Road No. 32, Shiyan 442000, Hubei Province, China. zhongji.meng@taihehospital.com |
| Key Words |
Curcumin; Hepatitis B virus; Covalently closed circular DNA; Histone deacetylation |
| Core Tip |
We showed that curcumin inhibited hepatitis B virus (HBV) replication and expression via reductions in covalently closed circular DNA-bound histone acetylation. Furthermore, siRNAs targeting HBV acted synergistically with curcumin, resulting in enhanced inhibition of HBV. |
| Publish Date |
2017-09-14 03:13 |
| Citation |
Wei ZQ, Zhang YH, Ke CZ, Chen HX, Ren P, He YL, Hu P, Ma DQ, Luo J, Meng ZJ. Curcumin inhibits hepatitis B virus infection by down-regulating cccDNA-bound histone acetylation. World J Gastroenterol 2017; 23(34): 6252-6260 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i34/6252.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i34.6252 |
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