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10/21/2017 7:10:38 AM | Browse: 398 | Download: 350
Publication Name World Journal of Gastroenterology
Manuscript ID 35260
Country/Territory Finland
Received
2017-07-31 00:19
Peer-Review Started
2017-07-31 00:59
To Make the First Decision
2017-08-15 03:40
Return for Revision
2017-08-16 09:27
Revised
2017-09-08 11:23
Second Decision
2017-09-15 00:06
Accepted by Journal Editor-in-Chief
2017-09-15 16:06
Accepted by Company Editor-in-Chief
2017-09-19 20:53
Articles in Press
2017-09-19 20:53
Publication Fee Transferred
2017-09-21 06:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-10-18 03:03
Publish the Manuscript Online
2017-10-21 07:10
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Case Report
Article Title Faecal microbiota transplantation in patients with Clostridium difficile and significant comorbidities as well as in patients with new indications: A case series
Manuscript Source Unsolicited Manuscript
All Author List Perttu Lahtinen, Eero Mattila, Veli-Jukka Anttila, Jyrki Tillonen, Matti Teittinen, Pasi Nevalainen, Seppo Salminen, Reetta Satokari and Perttu Arkkila
ORCID
Author(s) ORCID Number
Perttu Lahtinen http://orcid.org/0000-0001-6430-4642
Eero Mattila http://orcid.org/0000-0001-9787-7674
Veli-Jukka Anttila http://orcid.org/0000-0001-7734-9241
Jyrki Tillonen http://orcid.org/0000-0002-5661-9385
Matti Teittinen http://orcid.org/0000-0002-2268-7144
Pasi Nevalainen http://orcid.org/0000-0003-1172-9537
Seppo Salminen http://orcid.org/0000-0002-9737-7642
Reetta Satokari http://orcid.org/0000-0002-4258-3414
Perttu Arkkila http://orcid.org/0000-0003-2194-0424
Funding Agency and Grant Number
Corresponding author Perttu Lahtinen, MD, Department of Gastroenterology, Päijät-Häme Central Hospital, Keskussairaalankatu 7, Lahti 15610, Finland. perttupaavali@gmail.com
Keywords Faecal microbiota transplantation; Antibiotic resistance; Clostridium difficile infection; Microbiota; Immunodeficiency; Salmonella infection
Core Tip Knowledge of faecal microbiota transplantation (FMT) in immunocompromised patients and patients with conditions other than recurrent Clostridium difficile infection (rCDI) is scarce. We reviewed 13 FMT-treated patients with rCDI and major comorbidities as well as 8 patients with new indications. In our cohort, FMT appeared to be safe and effective for immuno­compromised patients: dialysis patients, human immu­nodeficiency virus patients, solid organ trans­plant patients and a patient with chronic lymphatic leuka­emia. Of the patients treated for indications other than rCDI, the most promising results were successful eradication of antibiotic-resistant bacteria. Eradication of chronic Salmonella carriage in two patients with FMT represents the first cases reported to date.
Publish Date 2017-10-21 07:10
Citation Lahtinen P, Mattila E, Anttila VJ, Tillonen J, Teittinen M, Nevalainen P, Salminen S, Satokari R, Arkkila P. Faecal microbiota transplantation in patients with Clostridium difficile and significant comorbidities as well as in patients with new indications: A case series. World J Gastroenterol 2017; 23(39): 7174-7184
Url http://www.wjgnet.com/1007-9327/full/v23/i39/7174.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i39.7174
Full Article (PDF) WJG-23-7174.pdf
Full Article (Word) WJG-23-7174.doc
Manuscript File 35260-Review.doc
Answering Reviewers 35260-Answering reviewers.pdf
Audio Core Tip 35260-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 35260-Conflict-of-interest statement.pdf
Copyright License Agreement 35260-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 35260-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 35260-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 35260-Language certificate.pdf
Supplementary Material 35260-Supplementary-Material-revision.doc
Peer-review Report 35260-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 35260-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 35260-Scientific misconduct check.pdf
Scientific Editor Work List 35260-Scientific editor work list.pdf