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9/26/2017 12:18:54 AM | Browse: 443 | Download: 299
Publication Name World Journal of Gastroenterology
Manuscript ID 35349
Country of Manuscript Source Italy
Received
2017-07-15 05:04
Peer-Review Started
2017-07-18 05:58
To Make the First Decision
2017-08-10 00:15
Return for Revision
2017-08-11 07:45
Revised
2017-08-21 11:31
Second Decision
2017-08-30 02:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-09-05 18:27
Articles in Press
2017-09-05 18:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-09-24 02:40
Publish the Manuscript Online
2017-09-25 08:56
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Review
Article Title Nonalcoholic fatty liver disease: Evolving paradigms
Manuscript Source Invited Manuscript
All Author List Amedeo Lonardo, Fabio Nascimbeni, Mauro Maurantonio, Alessandra Marrazzo, Luca Rinaldi and Luigi Elio Adinolfi
ORCID
Author(s) ORCID Number
Amedeo Lonardo http://orcid.org/0000-0001-9886-0698
Fabio Nascimbeni http://orcid.org/0000-0002-1051-1272
Mauro Maurantonio http://orcid.org/0000-0003-3500-1145
Alessandra Marrazzo http://orcid.org/0000-0001-5047-4042
Luca Rinaldi http://orcid.org/0000-0002-6541-3821
Luigi Elio Adinolfi http://orcid.org/0000-0001-8453-4912
Funding Agency and Grant Number
Correspondence To Luigi Elio Adinolfi, MD, Full Professor, Department of Medical, Surgical, Neurological, Geriatric, and Metabolic Sciences, University of Campania “Luigi Vanvitelli, Piazza Miraglia, Naples 80100, Italy. luigielio.adinolfi@unicampania.it
Keywords Nonalcoholic fatty liver disease; Biomarkers; Clinical correlates; Diagnosis; Epidemiology; Genetics; Liver histology; Management; Metabolic Syndrome; Pathogenesis; Screening; Type 2 diabetes
Core Tip Nonalcoholic fatty liver disease (NAFLD) is a pandemic disease. Recent evidence highlights new concepts in clinical and pathogenic heterogeneity of NAFLD, a systemic disorder with a multifactorial pathogenesis and protean clinical manifestations. Other than the classical obese phenotype of NAFLD, a lean though metabolically abnormal variant has been recognized. Simple steatosis is no more considered a benign condition; insulin resistance is necessary but not sufficient for the disease progression, and NAFLD is not only a mere hepatic manifestation of metabolic syndrome, but may forerun the development of metabolic syndrome and cardio-renal complications. Several non-invasive diagnostic tests are now available and new drug treatment options are coming.
Publish Date 2017-09-25 08:56
Citation Lonardo A, Nascimbeni F, Maurantonio M, Marrazzo A, Rinaldi L, Adinolfi LE. Nonalcoholic fatty liver disease: Evolving paradigms. World J Gastroenterol 2017; 23(36): 6571-6592
Url http://www.wjgnet.com/1007-9327/full/v23/i36/6571.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i36.6571
Full Article (PDF) WJG-23-6571.pdf
Full Article (Word) WJG-23-6571.doc
Manuscript File 35349-Review.docx
Answering Reviewers 35349-Answering reviewers.pdf
Audio Core Tip 35349-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 35349-Conflict-of-interest statement.pdf
Copyright License Agreement 35349-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 35349-Non-Native Speakers of English Editing Certificate.docx
Peer-review Report 35349-Peer-review(s).pdf
Scientific Misconduct Check 35349-Scientific misconduct check.pdf
Scientific Editor Work List 35349-Scientific editor work list.pdf