BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
12/27/2017 11:08:08 AM | Browse: 1045 | Download: 1413
Publication Name World Journal of Gastroenterology
Manuscript ID 35659
Country/Territory United States
Received
2017-07-30 03:16
Peer-Review Started
2017-07-30 15:19
To Make the First Decision
2017-08-30 03:18
Return for Revision
2017-09-04 07:19
Revised
2017-10-09 15:20
Second Decision
2017-11-07 08:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-11-07 18:30
Articles in Press
2017-11-07 18:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-11-16 01:01
Publish the Manuscript Online
2017-12-27 11:08
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Systematic Reviews
Article Title Fusobacterium’s link to colorectal neoplasia sequenced: A systematic review and future insights
Manuscript Source Unsolicited Manuscript
All Author List Hisham Hussan, Steven K Clinton, Kristen Roberts and Michael T Bailey
ORCID
Author(s) ORCID Number
Hisham Hussan http://orcid.org/0000-0002-8646-8370
Steven K Clinton http://orcid.org/0000-0002-2840-5865
Kristen Roberts http://orcid.org/0000-0001-5619-990X
Michael T Bailey http://orcid.org/0000-0002-2222-3980
Funding Agency and Grant Number
Corresponding Author Hisham Hussan, MD, Assistant Professor, Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, The Ohio State University Wexner Medical Center, 395 W 12th Ave, Suite 240, Columbus, OH 43210, United States. hisham.hussan@osumc.edu
Key Words Colon microbiota; Fusobacterium; Fusobacterium nucleatum; Colorectal cancer; Colorectal polyps; Carcinogenesis; Systematic; Review
Core Tip This is, to our knowledge, the first review to systematically examine the heterogeneous literature linking Fusobacterium to colorectal neoplasia. Accumulating evidence suggests that Fusobacterium, specifically Fusobacterium nucleatum (F. nucleatum), is more frequently detected in colorectal neoplasia, especially the pathway involving microsatellite instability. Multiple observational and animal experimental studies also suggest a procarcinogenic effect of F. nucleatum, likely due to activation of oncogenic and inflammatory pathways and modulation of the tumor immune environment. Virulence factors of F. nucleatum may contribute to its procarcinogenic effect. This information may be used to create novel strategies targeting colorectal cancer detection and chemoprevention.
Publish Date 2017-12-27 11:08
Citation Hussan H, Clinton SK, Roberts K, Bailey MT. Fusobacterium’s link to colorectal neoplasia sequenced: a systematic review and future insights. World J Gastroenterol 2017; 23(48): 8626-8650
URL http://www.wjgnet.com/1007-9327/full/v23/i48/8626.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i48.8626
Full Article (PDF) WJG-23-8626.pdf
Full Article (Word) WJG-23-8626.doc
Manuscript File 35659-Review.docx
Answering Reviewers 35659-Answering reviewers.pdf
Audio Core Tip 35659-Audio core tip.mp3
Biostatistics Review Certificate 35659-Biostatistics-Statement-revision.docx
Conflict-of-Interest Disclosure Form 35659-Conflict-of-interest statement.pdf
Copyright License Agreement 35659-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 35659-Language certificate.pdf
Supplementary Material 35659-supplemental.docx
Peer-review Report 35659-Peer-review(s).pdf
Scientific Editor Work List 35659-Scientific editor work list.pdf