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Articles Published Processes
10/29/2017 6:01:43 AM | Browse: 894 | Download: 1665
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Received |
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2017-08-05 05:12 |
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Peer-Review Started |
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2017-08-05 08:37 |
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To Make the First Decision |
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2017-08-14 23:59 |
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Return for Revision |
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2017-08-15 09:06 |
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Revised |
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2017-08-25 07:32 |
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Second Decision |
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2017-09-12 06:19 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2017-09-13 02:56 |
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Articles in Press |
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2017-09-13 02:56 |
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Publication Fee Transferred |
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2017-10-09 15:24 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-10-23 03:19 |
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Publish the Manuscript Online |
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2017-10-29 06:01 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Genetic associations with adverse events from anti-tumor necrosis factor therapy in inflammatory bowel disease patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Daniel Lew, Soon Man Yoon, Xiaofei Yan, Lori Robbins, Talin Haritunians, Zhenqiu Liu, Dalin Li and Dermot PB McGovern |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Daniel Lew, MD, Doctor, Internal Medicine, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, United States. daniel.lew@cshs.org |
| Key Words |
Genetic associations; Inflammatory bowel disease; Anti-tumor necrosis factor; Adverse events |
| Core Tip |
Tumor necrosis factor-α (TNF-α) plays a key role in the development and progression of inflammatory bowel disease (IBD). Anti-TNF therapy is highly efficacious in treating IBD patients, but many experience adverse events. Few studies have evaluated factors associated with adverse events to anti-TNF therapy. In this study, we found some genetic associations and pathways that are enriched for genes associated with the development of adverse events. Future studies will need to confirm these findings as the ability to identify subjects at high risk may help clinicians anticipate and therefore prevent or avoid these adverse events in the future. |
| Publish Date |
2017-10-29 06:01 |
| Citation |
Lew D, Yoon SM, Yan X, Robbins L, Haritunians T, Liu Z, Li D, McGovern DPB. Genetic associations with adverse events from anti-tumor necrosis factor therapy in inflammatory bowel disease patients. World J Gastroenterol 2017; 23(40): 7265-7273 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i40/7265.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i40.7265 |
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