Publication Name	World Journal of Transplantation
Manuscript ID	36014
Country	Norway

Received	2017-11-17 09:19
Peer-Review Started	2017-11-17 09:27
First Decision by Editorial Office Director	2017-11-29 20:27
Return for Revision	2017-12-01 00:54
Revised	2017-12-12 09:28
Publication Fee Transferred
Second Decision by Editor	2017-12-14 10:49
Second Decision by Editor-in-Chief	2017-12-14 11:45
Final Decision by Editorial Office Director	2017-12-28 19:26
Articles in Press	2017-12-28 19:26
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-02-08 14:59
Publish the Manuscript Online	2018-02-24 10:10

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Review
Article Title	Importance of physical capacity and the effects of exercise in heart transplant recipients
Manuscript Source	Invited Manuscript
All Author List	Marianne Yardley, Lars Gullestad and Kari Nytrøen
ORCID	Author(s) ORCID Number Marianne Yardley http://orcid.org/0000-0002-4827-4701 Lars Gullestad http://orcid.org/0000-0002-5932-6641 Kari Nytrøen http://orcid.org/0000-0002-4827-4700
Funding Agency and Grant Number
Corresponding Author	Kari Nytrøen, PhD, Doctor, Doctor, Senior Postdoctoral Fellow, Department of Cardiology, Oslo University Hospital Rikshospitalet, Postbox 4950 Nydalen, Oslo 0424, Norway. kari.nytroen@medisin.uio.no
Key Words	Heart transplantation; Exercise; High-intensity interval training; Peak oxygen uptake; Physical capacity; Prognosis; Survival; Inflammation; Angiogenesis
Core Tip	Despite the positive effects of regular exercise after a heart transplantation (HTx), HTx recipients’ physical capacity remains subnormal, and a strong association between physical capacity and survival has been demonstrated. Thus, the positive effects of high-intensity interval training (HIT) is a growing field of research, attracting worldwide focus and interest. Although the “HIT-effect” is not fully understood, a possible contributing factor is the increased levels of inflammatory mediators of angiogenesis generated during exercise. More high-quality research is strongly warranted, but ongoing studies already have the potential to change existing guidelines and contribute to a better prognosis for the HTx population.
Publish Date	2018-02-24 10:10
Citation	Yardley M, Gullestad L, Nytrøen K. Importance of physical capacity and the effects of exercise in heart transplant recipients. World J Transplant 2018; 8(1): 1-12
URL	http://www.wjgnet.com/2220-3230/full/v8/i1/1.htm
DOI	http://dx.doi.org/10.5500/wjt.v8.i1.1

Full Article (PDF)	WJT-8-1.pdf
Full Article (Word)	WJT-8-1.doc
Manuscript File	36014-Review.docx
Answering Reviewers	36014-Answering reviewers.pdf
Audio Core Tip	36014-Audio core tip.wav
Conflict-of-Interest Disclosure Form	36014-Conflict-of-interest statement.pdf
Copyright License Agreement	36014-Copyright assignment.pdf
Peer-review Report	36014-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	36014-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	36014-Scientific misconduct check.pdf
Scientific Editor Work List	36014-Scientific editor work list.pdf