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12/27/2017 10:31:19 AM | Browse: 1017 | Download: 1207
Publication Name World Journal of Hepatology
Manuscript ID 36107
Country United States
Received
2017-09-01 01:07
Peer-Review Started
To Make the First Decision
2017-09-25 08:06
Return for Revision
2017-10-09 13:18
Revised
2017-11-16 20:06
Second Decision
2017-11-28 08:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-12-07 01:47
Articles in Press
2017-12-07 01:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-12-22 01:23
Publish the Manuscript Online
2017-12-27 10:31
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Autoimmune hepatitis in the setting of human immunodeficiency virus infection: A case series
Manuscript Source Unsolicited Manuscript
All Author List Emmanuel Ofori, Daryl Ramai, Mel A Ona and Madhavi Reddy
ORCID
Author(s) ORCID Number
Emmanuel Ofori http://orcid.org/0000-0002-4373-0885
Daryl Ramai http://orcid.org/0000-0002-2460-7800
Mel A Ona http://orcid.org/0000-0002-5522-2124
Madhavi Reddy http://orcid.org/0000-0002-3359-1172
Funding Agency and Grant Number
Corresponding Author Daryl Ramai, MD, Research Fellow, Division of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Academic Affiliate of The Icahn School of Medicine at Mount Sinai, Clinical Affiliate of The Mount Sinai Hospital, 121 Dekalb Avenue, Brooklyn, NY 11201, United States. dramai@sgu.edu
Key Words Autoimmune hepatitis; Human immunodeficiency virus; Liver biopsy; Autoimmunity; Immunosuppression
Core Tip Liver damage is rarely caused by autoimmune disease in the setting of human immunodeficiency virus (HIV) infection. We describe a case series of two patients with a history of HIV, who presented with characteristic elevation in liver enzymes. Both patients were hepatitis C negative. Liver biopsies followed by histopathology confirmed the diagnosis of autoimmune hepatitis. Case 1 was treated by corticosteroids and azathioprine, while case 2 was treated by corticosteroids only. Both patients reported significant clinical improvement. This case suggests that liver biopsy should be performed in HIV patients with unknown liver disease. Additionally, it underscores the need for further clinical studies to explore the role of corticosteroids and immunosuppression in the management of autoimmune hepatitis in HIV patients.
Publish Date 2017-12-27 10:31
Citation Ofori E, Ramai D, Ona MA, Reddy M. Autoimmune hepatitis in the setting of human immunodeficiency virus infection: A case series. World J Hepatol 2017; 9(36): 1367-1371 Available from: URL: http://www.wjgnet.com/1948-5182/full/v9/i36/1367.htm DOI: http://dx.doi.org/10.4254/wjh.v9.i36.1367
URL http://www.wjgnet.com/1948-5182/full/v9/i36/1367.htm
DOI http://dx.doi.org/10.4254/wjh.v9.i36.1367
Full Article (PDF) WJH-9-1367.pdf
Full Article (Word) WJH-9-1367.doc
Manuscript File 36107-Review.doc
Answering Reviewers 36107-Answering reviewers.pdf
Audio Core Tip 36107-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 36107-Conflict-of-interest statement.pdf
Copyright License Agreement 36107-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 36107-Signed-Informed-Consent-Form(s)-or-Document(s)-revision.pdf
Supplementary Material 36107-Supplementary-Material-revision.pdf
Peer-review Report 36107-Peer-review(s).pdf
Scientific Misconduct Check 36107-Scientific misconduct check.pdf
Scientific Editor Work List 36107-Scientific editor work list.pdf