ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Fecal microbiota transplantation induced remission of infantile allergic colitis through microecology re-establishment
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Sheng-Xuan Liu, Yin-Hu Li, Wen-Kui Dai, Xue-Song Li, Chuang-Zhao Qiu, Meng-Ling Ruan, Biao Zou, Chen Dong, Yan-Hong Liu, Jia-Yi He, Zhi-Hua Huang and Sai-Nan Shu |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Clinical Key Specialty Construction Project (Pediatric Digestive Disease) |
[2011]873 |
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Corresponding Author |
Sai-Nan Shu, MD, Associate Professor, Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Road, Wuhan 430030, Hubei Province, China. snshu@tjh.tjmu.edu.cn |
Key Words |
Pediatric; Infantile allergic colitis; Fecal microbiota transplantation; Gut microbiota; Immune reaction |
Core Tip |
This retrospective study explored the therapeutic effects and safety of fecal microbiota transplantation (FMT) treatment on 19 allergic colitis (AC) infants who were younger than 1-year-old. After FMT treatment, AC symptoms were relieved in the patients rapidly, and no patient relapsed within 15 mo. With gut microbiota (GM) analysis, 6/10 patients exhibited higher microbial diversity after FMT treatment. Moreover, decreased Proteobacteria and increased Firmicutes supplied the hints of GM re-establishment in the patients after FMT treatment. Therefore, this work showed the curative effects of FMT to the AC infants and its possible mechanism. |
Publish Date |
2017-12-27 11:08 |
Citation |
Liu SX, Li YH, Dai WK, Li XS, Qiu CZ, Ruan ML, Zou B, Dong C, Liu YH, He JY, Huang ZH, Shu SN. Fecal microbiota transplantation induces remission of infantile allergic colitis through gut microbiota re-establishment. World J Gastroenterol 2017; 23(48): 8570-8581 |
URL |
http://www.wjgnet.com/1007-9327/full/v23/i48/8570.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v23.i48.8570 |