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Articles Published Processes
1/7/2018 4:21:05 AM | Browse: 1436 | Download: 2857
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Received |
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2017-10-29 02:27 |
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Peer-Review Started |
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2017-10-29 06:00 |
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First Decision by Editorial Office Director |
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2017-11-14 19:36 |
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Return for Revision |
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2017-11-16 08:07 |
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Revised |
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2017-11-22 14:43 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2017-11-27 10:06 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2017-11-27 20:08 |
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Articles in Press |
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2017-11-27 20:08 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-12-25 15:37 |
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Publish the Manuscript Online |
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2018-01-07 04:21 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Observational Study |
| Article Title |
HLA-DQ: Celiac disease vs inflammatory bowel disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Marta M Bosca-Watts, Miguel Minguez, Dolores Planelles, Samuel Navarro, Alejandro Rodriguez, Jesus Santiago, Joan Tosca and Francisco Mora |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Carlos III Institute |
CM07/00240 |
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| Corresponding Author |
Marta M Bosca-Watts, MD, PhD, Attending Doctor, Research Scientist, Staff Physician, IBD Unit, Digestive Disease Department of the University Clinic Hospital of Valencia, University of Valencia, C/ Blasco Ibañez 17, Valencia 46010, Spain. inflamatoriahcuv@gmail.com |
| Key Words |
Genetic predisposition; Celiac disease; Inflammatory bowel disease; Crohn’s disease; Human leucocyte antigen; Ulcerative colitis |
| Core Tip |
The higher risk for celiac disease (CeD) in inflammatory bowel disease (IBD) is controversial. Since the involvement of human leucocyte antigen (HLA)-DQ2 and -DQ8 antigens (HLA-CeD) in the susceptibility to CeD is clearly established and it has been accepted as a useful test to exclude CeD, we determined the frequency of HLA-CeD in IBD patients. We observed that HLA-CeD is not more frequent in IBD patients, with an even lower frequency of HLA-DQ2 and -DQ8 in ulcerative colitis and Crohn’s disease respectively. On the other hand, HLA-DQ2.2 was present in 34% of the Crohn’s disease patients and may constitute a genetic risk factor. |
| Publish Date |
2018-01-07 04:21 |
| Citation |
Bosca-Watts MM, Minguez M, Planelles D, Navarro S, Rodriguez A, Santiago J, Tosca J, Mora F. HLA-DQ: Celiac disease vs inflammatory bowel disease. World J Gastroenterol 2018; 24(1): 96-103
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| URL |
http://www.wjgnet.com/1007-9327/full/v24/i1/96.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i1.96 |
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