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Articles Published Processes
9/11/2014 3:07:00 PM | Browse: 870 | Download: 812
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Received |
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2013-05-14 09:47 |
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Peer-Review Started |
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2013-05-14 15:46 |
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To Make the First Decision |
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2013-06-09 10:15 |
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Return for Revision |
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2013-06-18 13:18 |
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Revised |
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2013-06-29 01:09 |
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Second Decision |
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2013-07-05 11:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-07-05 13:13 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-09-15 10:37 |
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Publish the Manuscript Online |
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2013-11-17 20:09 |
Category |
Urology & Nephrology |
Manuscript Type |
Editorial |
Article Title |
Mirabegron, a novel, non-antimuscarinic drug for the overactive bladder: An up-to-dated review
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Manuscript Source |
Invited Manuscript |
All Author List |
Emilio Sacco and Riccardo Bientinesi |
Funding Agency and Grant Number |
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Corresponding Author |
Emilio Sacco, MD, PhD, Urologic Clinic, “Agostino Gemelli” Hospital, Catholic University Medical School of Rome, Largo F Vito 1, 00168 Rome, Italy. emilio.sacco@gmail.com |
Key Words |
Mirabegron; β3-adrenoceptor agonist; Antimuscarinics; Overactive bladder; Urinary incontinence |
Core Tip |
Mirabegron is a first-in-class, potent β3-adreno?ceptors agonist that has been proven effective in the treatment of overactive bladder (OAB) based on multiple randomized multinational trials. The safety-tolerability profile of treatment with mirabegron has been extensively studied. The placebo-like incidence of classic adverse effects caused by antimuscarinics should improve long-term adherence to treatment with this new drug. Mirabegron can be an alternative in patients with contraindications to antimuscarinics or that discontinued previous antimuscarinic therapy. An updated review of the rationale of β3-agonism for OAB treatment and evidence of efficacy and safety of mirabegron is presented. |
Publish Date |
2013-11-17 20:09 |
Citation |
Sacco E, Bientinesi R. Mirabegron, a novel, non-antimuscarinic drug for the overactive bladder: An up-to-dated review. World J Obstet Gynecol 2013; 2(4): 65-73 |
URL |
http://www.wjgnet.com/2218-6220/full/v2/i4/65.htm |
DOI |
http://dx.doi.org/10.5317/wjog.v2.i4.65 |
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