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Articles Published Processes
12/20/2017 2:49:19 AM | Browse: 1273 | Download: 1147
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Received |
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2017-10-24 03:28 |
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Peer-Review Started |
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2017-10-24 11:47 |
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To Make the First Decision |
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2017-11-08 03:15 |
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Return for Revision |
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2017-11-08 07:54 |
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Revised |
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2017-11-14 20:46 |
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Second Decision |
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2017-12-04 08:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-12-04 19:56 |
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Articles in Press |
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2017-12-04 19:56 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-12-11 05:19 |
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Publish the Manuscript Online |
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2017-12-20 02:49 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Minireviews |
Article Title |
Obese children with fatty liver: Between reality and disease mongering
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Manuscript Source |
Invited Manuscript |
All Author List |
Giusy Ranucci, Maria Immacolata Spagnuolo and Raffaele Iorio |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Raffaele Iorio, MD, Associate Professor, Department of Translational Medical Science, Section of Pediatrics, University Federico II, Via Pansini 5, Naples 80131, Italy. riorio@unina.it |
Key Words |
Obesity; Children; Non alcoholic fatty liver disease; Non alcoholic steatohepatitis; Cirrhosis; Liver transplant; Disease mongering |
Core Tip |
The number of obese children with nonalcoholic fatty liver with a documented poor outcome is small in spite of the alarming tones used in some papers. The available studies are insufficient to determine whether or not children with nonalcoholic fatty liver have an elevated risk of developing detrimental health conditions. Large-scale longitudinal studies with long-term follow-up of children with nonalcoholic fatty liver are desirable. Since most obese children are not adherent to lifestyle modifications and hypocaloric diets, there is a growing number of studies on pharmacological interventions with the risk of disease mongering, the practice of widening the boundaries of illness in order to expand the markets for treatment. The studies on ancillary pharmacological interventions, in addition to diet and exercise, have been performed in few children with inconclusive and conflicting results. The proposal to the obese patient of an ancillary drug may divert his attention from the diet and exercise. |
Publish Date |
2017-12-20 02:49 |
Citation |
Ranucci G, Spagnuolo MI, Iorio R. Obese children with fatty liver: Between reality and disease mongering. World J Gastroenterol 2017; 23(47): 8277-8282 |
URL |
http://www.wjgnet.com/1007-9327/full/v23/i47/8277.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v23.i47.8277 |
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