Publication Name	World Journal of Virology
Manuscript ID	36851
Country	Germany

Received	2017-10-27 01:40
Peer-Review Started	2017-10-27 08:33
To Make the First Decision	2017-11-23 02:23
Return for Revision	2017-11-24 03:00
Revised	2017-12-04 17:26
Second Decision	2017-12-08 10:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-12-13 20:44
Articles in Press	2017-12-13 20:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-01-29 09:58
Publish the Manuscript Online	2018-02-08 07:53

ISSN	2220-3249 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Virology
Manuscript Type	Basic Study
Article Title	Identification of various cell culture models for the study of Zika virus
Manuscript Source	Unsolicited Manuscript
All Author List	Kiyoshi Himmelsbach and Eberhard Hildt
ORCID	Author(s) ORCID Number Kiyoshi Himmelsbach http://orcid.org/0000-0002-1840-6012 Eberhard Hildt http://orcid.org/0000-0002-3020-9564
Funding Agency and Grant Number	Funding Agency Grant Number Federal Ministry of Health (BMG) to Hildt E
Corresponding Author	Eberhard Hildt, PhD, Professor, Department of Virology, Paul-Ehrlich-Institut, Paul-Ehrlich-Str. 51-59, Langen 63225, Germany. eberhard.hildt@pei.de
Key Words	Zika virus; Cell lines; Quantitative real-time PCR; Plaque assay; Interferon
Core Tip	In this study ten different cell lines, human and non-human, from various tissues (e.g., hepatocytes, keratinocytes and neuronal cells) were tested upon their susceptibility to Zika virus (ZIKV) infection. Except CHO cells all cells supported ZIKV life cycle, but differed in parts strongly in the intracellular and released amount of infectious viral particles. Investigating the interferon response showed no clear correlation between high and low producer cell lines.
Publish Date	2018-02-08 07:53
Citation	Himmelsbach K, Hildt E. Identification of various cell culture models for the study of Zika virus. World J Virol 2018; 7(1): 10-20
URL	http://www.wjgnet.com/2220-3249/full/v7/i1/10.htm
DOI	http://dx.doi.org/10.5501/wjv.v7.i1.10

Full Article (PDF)	WJV-7-10.pdf
Full Article (Word)	WJV-7-10.doc
Manuscript File	36851-Review.docx
Answering Reviewers	36851-Answering reviewers.pdf
Audio Core Tip	36851-Audio core tip.mp3
Biostatistics Review Certificate	36851-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	36851-Conflict-of-interest statement.pdf
Copyright License Agreement	36851-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	36851-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	36851-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	36851-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	36851-Non-Native Speakers of English Editing Certificate.docx
Peer-review Report	36851-Peer-review(s).pdf
Scientific Misconduct Check	36851-Scientific misconduct check.pdf
Scientific Editor Work List	36851-Scientific editor work list.pdf