Publication Name	World Journal of Gastroenterology
Manuscript ID	36872
Country	Hungary

Received	2017-10-27 09:16
Peer-Review Started	2017-10-28 10:18
To Make the First Decision	2017-11-22 00:53
Return for Revision	2017-11-27 09:12
Revised	2017-11-28 12:20
Second Decision	2017-12-04 09:18
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-12-04 19:51
Articles in Press	2017-12-04 19:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-12-05 08:56
Publish the Manuscript Online	2017-12-12 08:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Relation of the IGF/IGF1R system to autophagy in colitis and colorectal cancer
Manuscript Source	Invited Manuscript
All Author List	Ferenc Sipos, Hajnal Székely, Imre Dániel Kis, Zsolt Tulassay and Gyorgyi Muzes
ORCID	Author(s) ORCID Number Ferenc Sipos http://orcid.org/0000-0002-2767-7746 Hajnal Székely http://orcid.org/0000-0001-7024-6944 Imre Dániel Kis http://orcid.org/0000-0001-5012-7083 Zsolt Tulassay http://orcid.org/0000-0003-2452-6640 Gyorgyi Muzes http://orcid.org/0000-0002-9099-0372
Funding Agency and Grant Number	Funding Agency Grant Number Hungarian Scientific Research Fund OTKA-K111743
Corresponding Author	Ferenc Sipos, MD, PhD, Assistant Professor, Immunology and Medicine, 2nd Department of Internal Medicine, Semmelweis University, Szentkiralyi street 46, Budapest 1088, Hungary. sipos.ferenc@med.semmelweis-univ.hu
Key Words	Insulin-like growth factor; IGF1R; Autophagy; Colitis; Colorectal cancer; Metabolic syndrome
Core Tip	Targeting the insulin-like growth factor 1 receptor (IGF1R)-autophagy crosstalk could represent a promising strategy for the development of new antiinflammatory and anticancer therapies, and may help for subjects suffering from metabolic syndrome who are at increased risk of colorectal cancer. However, cautiousness is also required, because pharmacologic IGF1R modulation can initiate additional, sometimes unfavorable biologic effects.
Publish Date	2017-12-12 08:34
Citation	Sipos F, Székely H, Kis ID, Tulassay Z, Műzes G. Relation of the IGF/IGF1R system to autophagy in colitis and colorectal cancer. World J Gastroenterol 2017; 23(46): 8109-8119
URL	http://www.wjgnet.com/1007-9327/full/v23/i46/8109.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i46.8109

Full Article (PDF)	WJG-23-8109.pdf
Full Article (Word)	WJG-23-8109.doc
Manuscript File	36872-Review.docx
Answering Reviewers	36872-Answering reviewers.pdf
Audio Core Tip	36872-Audio core tip.wav
Conflict-of-Interest Disclosure Form	36872-Conflict-of-interest statement.pdf
Copyright License Agreement	36872-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	36872-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	36872-Language certificate.pdf
Peer-review Report	36872-Peer-review(s).pdf
Scientific Editor Work List	36872-Scientific editor work list.pdf