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Articles Published Processes
2/9/2018 7:24:29 AM | Browse: 1104 | Download: 1017
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Received |
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2017-11-06 08:59 |
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Peer-Review Started |
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2017-11-07 09:42 |
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To Make the First Decision |
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2017-11-30 06:03 |
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Return for Revision |
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2017-12-01 09:20 |
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Revised |
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2017-12-11 01:59 |
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Second Decision |
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2017-12-19 11:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2017-12-20 02:18 |
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Articles in Press |
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2017-12-20 02:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-02-08 08:03 |
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Publish the Manuscript Online |
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2018-02-09 07:24 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Daniel Brungs, David Lynch, Alison WS Luk, Elahe Minae, Marie Ranson, Morteza Aghmesheh, Kara L Vine, Martin Carolan, Mouhannad Jaber, Paul de Souza and Therese Becker |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Daniel Brungs, BSc, MBBS, Doctor, Illawarra Cancer Care Centre, Wollongong Hospital, Crown St, Wollongong 2500, Australia. daniel.brungs@health.nsw.gov.au |
| Key Words |
Cryopreservation; Circulating tumor cells; Liquid biopsy; Gastroesophageal cancer; Gastric cancer |
| Core Tip |
This study demonstrates a novel and robust protocol for the cryopreservation and thawing of patient blood samples, demonstrating reliable circulating tumor cell isolation and characterisation after the long term storage of patient samples. Using the largest patient cohort reported to date, we validated our method by confirming the independent prognostic association of circulating tumor cell (CTC) enumeration from cryopreserved peripheral blood mononuclear cells. Cryopreservation may assist with the wider incorporation of CTC collection and analysis in biobanking, retrospective studies, and large international clinical trials, by facilitating specimen storage, bulk transporting, and batch processing. |
| Publish Date |
2018-02-09 07:24 |
| Citation |
Brungs D, Lynch D, Luk AW, Minaei E, Ranson M, Aghmesheh M, Vine KL, Carolan M, Jaber M, de Souza P, Becker TM. Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer. World J Gastroenterol 2018; 24(7): 810-818 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i7/810.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i7.810 |
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