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3/26/2018 8:48:04 AM | Browse: 365 | Download: 309
Publication Name World Journal of Gastroenterology
Manuscript ID 37107
Country/Territory United States
Received
2017-12-04 09:09
Peer-Review Started
2017-12-04 10:01
To Make the First Decision
2017-12-13 02:46
Return for Revision
2017-12-14 08:30
Revised
2018-03-16 07:46
Second Decision
2018-03-16 10:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-03-18 01:45
Articles in Press
2018-03-18 01:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-03-23 09:14
Publish the Manuscript Online
2018-03-26 08:48
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models
Manuscript Source Invited Conference Manuscripts
All Author List Nicha Wongjarupong, Gabriela M Negron-Ocasio, Roongruedee Chaiteerakij, Benyam Addissie, Essa Mohamed, Kristin C Mara, William S Harmsen, Paul J Theobald, Brian E Peters, Joseph G Balsanek, Melissa M Ward, Nasra Giama, Sudhakar Kundapur Venkatesh, Denise M Harnois, Michael R Charlton, Hiroyuki Yamada, Alicia Algeciras-Schimnich, Melissa R Snyder, Terry M Therneau and Lewis R. Roberts
ORCID
Author(s) ORCID Number
Nicha Wongjarupong http://orcid.org/0000-0001-8676-413X
Gabriela M Negron-Ocasio http://orcid.org/0000-0002-8484-8601
Roongruedee Chaiteerakij http://orcid.org/0000-0002-7191-3881
Benyam Addissie http://orcid.org/0000-0000-0000-0002
Essa Mohamed http://orcid.org/0000-0002-0307-6241
Kristin C Mara http://orcid.org/0000-0001-9824-6049
William S Harmsen http://orcid.org/0000-0001-7134-5362
Paul J Theobald http://orcid.org/0000-0002-5730-8925
Brian E Peters http://orcid.org/0000-0003-2485-0766
Joseph G Balsanek http://orcid.org/0000-0003-2929-2871
Melissa M Ward http://orcid.org/0000-0001-9784-9518
Nasra Giama http://orcid.org/0000-0003-2764-866X
Sudhakar Kundapur Venkatesh http://orcid.org/0000-0002-7514-1030
Denise M Harnois http://orcid.org/0000-0000-0000-0007
Michael R Charlton http://orcid.org/0000-0002-8766-7494
Hiroyuki Yamada http://orcid.org/0000-0002-1827-3758
Alicia Algeciras-Schimnich http://orcid.org/0000-0002-4455-6217
Melissa R Snyder http://orcid.org/0000-0002-5442-4699
Terry M Therneau http://orcid.org/0000-0003-1490-6711
Lewis R. Roberts http://orcid.org/0000-0001-7885-8574
Funding Agency and Grant Number
Funding Agency Grant Number
Mayo Clinic Center for Cell Signaling in Gastroenterology NIDDK P30DK084567
Mayo Clinic Center for Clinical and Translational Science NCATS UL1 TR000135
Wako Life Sciences, Inc.
Corresponding author Lewis R. Roberts, MD, PhD, Doctor, Full Professor, Professor, Research Fellow, Professor of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, 200 First Street SW, Rochester, MN55905, United States. roberts.lewis@mayo.edu
Keywords alpha-fetoprotein; AFP-L3; des-gamma-carboxyprothrombin; BALAD; BALAD-2; Hepatocellular carcinoma; Liver transplant; Recurrence; Outcome
Core Tip BALAD score and BALAD-2 class incorporating alpha-fetoprotein (AFP), AFP-L3, and des-gamma-carboxyprothrombin are used to predict survival of patients with hepatocellular carcinoma. However, there were limited numbers of patients who received liver transplant in previous cohorts in which performance of the BALAD was studied. Our study showed that pre-transplant BALAD score and BALAD-2 class are useful for predicting outcome of hepatocellular carcinoma patients receiving liver transplant. However, a more predictive model uses the combination of all three biomarkers using the cut-offs from the BALAD score along with maximum tumor size at the time of transplant.
Publish Date 2018-03-26 08:48
Citation Wongjarupong N, Negron-Ocasio GM, Chaiteerakij R, Addissie BD, Mohamed EA, Mara KC, Harmsen WS, Theobald PJ, Peters BE, Balsanek JG, Ward MM, Giama NH, Venkatesh SK, Harnois DM, Charlton MR, Yamada H, Algeciras-Schimnich A, Snyder MR, Therneau TM, Roberts LR. Pre-transplant tumor biomarkers show more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models. World J Gastroenterol 2018; 24(12): 1321-1331
Url http://www.wjgnet.com/1007-9327/full/v24/i12/1321.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i12.1321
Full Article (PDF) WJG-24-1321.pdf
Full Article (Word) WJG-24-1321.doc
Manuscript File 37107-Review.docx
Answering Reviewers 37107-Answering reviewers.pdf
Audio Core Tip 37107-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 37107-Conflict-of-interest statement.pdf
Copyright License Agreement 37107-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 37107-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 37107-Institutional review board statement.pdf
Supplementary Material 37107-Supplementary material.pdf
Peer-review Report 37107-Peer-review(s).pdf
Scientific Misconduct Check 37107-Scientific misconduct check.pdf
Scientific Editor Work List 37107-Scientific editor work list.pdf