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Articles Published Processes
3/5/2018 11:23:39 AM | Browse: 977 | Download: 1159
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Received |
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2017-11-15 17:09 |
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Peer-Review Started |
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2017-11-16 08:14 |
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To Make the First Decision |
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2017-12-20 07:33 |
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Return for Revision |
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2017-12-21 10:47 |
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Revised |
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2017-12-26 16:14 |
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Second Decision |
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2018-01-15 08:17 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-01-15 20:36 |
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Articles in Press |
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2018-01-15 20:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-01-20 11:34 |
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Typeset the Manuscript |
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2018-03-03 12:31 |
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Publish the Manuscript Online |
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2018-03-05 11:23 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
Long noncoding RNA RP4 functions as a competing endogenous RNA through miR-7-5p sponge activity in colorectal cancer
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Mu-Lin Liu, Qiao Zhang, Xiao Yuan, Long Jin, Li-Li Wang, Tao-Tao Fang and Wen-Bin Wang |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Scientific Research Foundation of Anhui Education Department |
KJ2017A219 |
Scientific Research Foundation of Academic Leader of Anhui Province |
2016H105 |
Education Talent Foundation of Universities of Anhui Education Department |
gxbjZD2016070 |
National Natural Science Foundation of China |
81500373 |
Natural Science Foundation of Anhui Province |
1608085MH193 |
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Corresponding Author |
Wen-Bin Wang, PhD, Doctor, Doctor, Professor, Department of General Surgery, The Fourth Affiliated Hospital of Anhui Medical University, No. 372, Tunxi Road, Hefei 230022, Anhui Province, China. surdoctor@163.com |
Key Words |
Colorectal cancer; long noncoding RNA RP4; SH3GLB1; miR-7-5p; competing endogenous RNA |
Core Tip |
In the present study, we investigated the role of long noncoding RNA (lncRNA) RP4 in colorectal cancer using an in vivo cell model and an in vivo xenograft model. Mechanistic analysis suggested that lncRNA RP4 functions in colorectal cancer pathogenesis as a competing endogenous RNA that regulates SH3GLB1 expression by acting as a sponge for miR-7-5p. It could also serve as a potential therapeutic target for colorectal cancer treatment. |
Publish Date |
2018-03-05 11:23 |
Citation |
Liu ML, Zhang Q, Yuan X, Jin L, Wang LL, Fang TT, Wang WB. Long noncoding RNA RP4 functions as a competing endogenous RNA through miR-7-5p sponge activity in colorectal cancer. World J Gastroenterol 2018; 24(9): 1004-1012 |
URL |
http://www.wjgnet.com/1007-9327/full/v24/i9/1004.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v24.i9.1004 |
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