BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
2/6/2018 3:22:41 AM | Browse: 454 | Download: 341
Publication Name World Journal of Gastroenterology
Manuscript ID 37325
Country/Territory Thailand
2017-12-05 19:10
Peer-Review Started
2017-12-06 08:47
To Make the First Decision
2017-12-20 07:39
Return for Revision
2017-12-21 12:18
2018-01-05 19:34
Second Decision
2018-01-19 09:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-01-19 18:41
Articles in Press
2018-01-19 18:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-01-31 10:08
Publish the Manuscript Online
2018-02-06 03:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Authors 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title High prevalence of hepatitis B-antibody loss and a case report of de novo hepatitis B virus infection in a child after living-donor liver transplantation
Manuscript Source Invited Conference Manuscripts
All Author List Palittiya Sintusek, Nawarat Posuwan, Piyaporn Wanawongsawad, Suttiruk Jitraruch, Yong Poovorawan and Voranush Chongsrisawat
Author(s) ORCID Number
Palittiya Sintusek http://orcid.org/0000000344410151
Nawarat Posuwan http://orcid.org/0000000270221541
Piyaporn Wanawongsawad http://orcid.org/0000000172598441
Suttiruk Jitraruch http://orcid.org/0000000327662453
Yong Poovorawan http://orcid.org/0000000223376807
Voranush Chongsrisawat http://orcid.org/0000-0002-6106-0504
Funding Agency and Grant Number
Funding Agency Grant Number
Grants for development of New Faculty Staff, Ratchadaphiseksomphot Endowment Fund
The Special Task Force for Activating Research in Immune Response in Children with Chronic Liver Diseases and Children after Liver Transplantation
Research Chair Grant from the National Science and Technology Development Agency P-15-50004
The Center of Excellence in Clinical Virology, Chulalongkorn Unversity and King Chulalongkorn Memorial Hospital GCE 5900930-005
Corresponding author Voranush Chongsrisawat, MD, Lecturer, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, 1873, Rama 4 Road, Pathumwan, Bangkok 10330, Thailand. voranush.c@chula.ac.th
Key Words Hepatitis B vaccine; Liver transplantation; De novo hepatitis B infection; Anti-HBs antibody; Immunity
Core Tip Despite the completion of hepatitis B vaccination (HBV), loss of hepatitis B immunity in children after liver transplantation is common and we encountered a case of de novo HBV infection following liver transplantation. Serum anti-HBs, albumin, total bilirubin, and direct bilirubin prior to liver transplantation were identified as potential factors related to HBV immunity loss after liver transplantation. A booster dose of hepatitis B vaccine and raising serum albumin to normal levels could delay the rapid loss of HBV immunity after liver transplantation but may not prevent de novo hepatitis B. Consequently, strategies are required to maintain anti-HBs antibody above the protective level after liver transplantation. Regular assessment of anti-HBs after liver transplantation should also be considered along with revaccination to guarantee long-term protection from HBV infection.
Publish Date 2018-02-06 03:22
Citation Sintusek P, Posuwan N, Wanawongsawad P, Jitraruch S, Poovorawan Y, Chongsrisawat V. High prevalence of hepatitis B-antibody loss and a case report of de novo hepatitis B virus infection in a child after living-donor liver transplantation. World J Gastroenterol 2018; 24(6): 752-762
Url http://www.wjgnet.com/1007-9327/full/v24/i6/752.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i6.752
Full Article (PDF) WJG-24-752.pdf
Full Article (Word) WJG-24-752.doc
Manuscript File 37325-Review.docx
Answering Reviewers 37325-Answering reviewers.pdf
Audio Core Tip 37325-Audio core tip.mp3
Biostatistics Review Certificate 37325-Biostatistics Review Certificate.pdf
Conflict-of-Interest Disclosure Form 37325-Conflict-of-interest statement.pdf
Copyright License Agreement 37325-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 37325-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 37325-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 37325-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 37325-Language certificate.pdf
Peer-review Report 37325-Peer-review(s).pdf
Scientific Misconduct Check 37325-Scientific misconduct check.pdf
Scientific Editor Work List 37325-Scientific editor work list.pdf