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Articles Published Processes
4/27/2018 3:25:40 AM | Browse: 1202 | Download: 1137
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Received |
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2017-12-05 16:15 |
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Peer-Review Started |
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2017-12-05 16:46 |
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To Make the First Decision |
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2018-01-17 01:26 |
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Return for Revision |
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2018-01-18 06:09 |
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Revised |
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2018-03-06 15:04 |
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Second Decision |
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2018-03-30 10:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-03-30 19:03 |
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Articles in Press |
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2018-03-30 19:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-04-25 11:13 |
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Publish the Manuscript Online |
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2018-04-27 03:25 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
High tacrolimus intra-patient variability is associated with graft rejection, and de novo donor-specific antibodies occurrence after liver transplantation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Arnaud Del Bello, Nicolas Congy-Jolivet, Marie Danjoux, Fabrice Muscari, Laurence Lavayssière, Laure Esposito, Anne-Laure Hebral, Julie Bellière and Nassim Kamar |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Arnaud Del Bello, MD, Doctor, Doctor, Department of Nephrology and Organ Transplantation, CHU Rangueil, TSA 50032, Cedex 9,, Toulouse 31059, France. delbello.a@chu-toulouse.fr |
| Key Words |
Variability; Liver transplantation; Donor-specific antibodies; Immunosuppression |
| Core Tip |
Tacrolimus intra-patient variability (Tac IPV) was associated with kidney-graft rejection and worse long-term outcomes, but until now, was not well studied after liver transplantation in adult recipients. We found that the coefficient of variability-IPV of tacrolimus was a predictive factor for acute rejection and the occurrence of de novo donor-specific antibodies (DSA) after liver transplantation in a retrospective cohort of 116 recipients treated with tacrolimus and mycophenolate mofetil. This could be a useful tool to identify patients with a greater risk of graft rejection and of developing a de novo DSA after liver transplantation. |
| Publish Date |
2018-04-27 03:25 |
| Citation |
Del Bello A, Congy-Jolivet N, Danjoux M, Muscari F, Lavayssière L, Esposito L, Hebral AL, Bellière J, Kamar N. High tacrolimus intra-patient variability is associated with graft rejection, and de novo donor-specific antibodies occurrence after liver transplantation. World J Gastroenterol 2018; 24(16): 1795-1802 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i16/1795.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i16.1795 |
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