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Articles Published Processes
2/9/2018 7:24:29 AM | Browse: 1253 | Download: 2063
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Received |
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2017-12-06 17:05 |
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Peer-Review Started |
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To Make the First Decision |
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2017-12-12 02:46 |
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Return for Revision |
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2017-12-12 08:05 |
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Revised |
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2017-12-13 16:16 |
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Second Decision |
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2017-12-19 11:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-12-20 02:12 |
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Articles in Press |
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2017-12-20 02:12 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-02-08 08:03 |
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Publish the Manuscript Online |
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2018-02-09 07:24 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Glucose transporter expression in the human colon
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Flavia Merigo, Alessandro Brandolese, Sonia Facchin, Silvia Missaggia, Paolo Bernardi, Federico Boschi, Renata D'Incà, Edoardo Vincenzo Savarino, Andrea Sbarbati and Giacomo Carlo Sturniolo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Flavia Merigo, BSc, Human Anatomy and Histology Section, Department of Neuroscience, Biomedicine and Movement, Human Anatomy and Histology Section, University of Verona, Strada Le Grazie, 8, Verona 37134, Italy. flavia.merigo@univr.it |
| Key Words |
Ulcerative colitis; Colon; Crohn’s disease; Glucose transporter; LYVE-1, Immunohistochemistry |
| Core Tip |
Our study demonstrates that GLUT2, SGLT1, and GLUT5 glucose transporters are expressed in the colorectal mucosa in controls and patients with inflammatory bowel disease (IBD). In addition, it provides first evidence that GLUT5 expression is associated with lymphatic vessels in controls and IBD patients. GLUT5-immunoreactive vessels were isolated or clustered in specific areas. We interpreted the presence of clusters as a pattern related to proliferative zones. As GLUT5 is the main fructose transporter, fructose may have a role in the atypical aggregation of lymphatic vessels. This novel finding yields further insight into the characterization of lymphatic vasculature, whose dysfunction is a long-recognized feature in humans with IBD. |
| Publish Date |
2018-02-09 07:24 |
| Citation |
Merigo F, Brandolese A, Facchin S, Missaggia S, Bernardi P, Boschi F, D’Incà R, Savarino EV, Sbarbati A, Sturniolo GC. Glucose transporter expression in the human colon. World J Gastroenterol 2018; 24(7): 775-793 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i7/775.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i7.775 |
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