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Articles Published Processes
9/1/2014 4:06:00 PM | Browse: 1238 | Download: 1401
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Received |
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2013-05-26 07:42 |
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Peer-Review Started |
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2013-05-26 19:09 |
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To Make the First Decision |
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2013-06-24 10:26 |
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Return for Revision |
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2013-07-01 13:41 |
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Revised |
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2013-07-08 23:25 |
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Second Decision |
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2013-08-16 19:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-08-17 00:36 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-08-26 13:47 |
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Publish the Manuscript Online |
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2013-09-14 11:34 |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Editorial |
Article Title |
Obesity, insulin resistance, adipocytokines and breast cancer: New biomarkers and attractive therapeutic targets
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Manuscript Source |
Invited Manuscript |
All Author List |
Maria Dalamaga |
Funding Agency and Grant Number |
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Corresponding Author |
Maria Dalamaga, MD, PhD, MS, MPH, Assistant Professor, Department of Clinical Biochemistry, Medical School, University of Athens, “Attikon” General University Hospital, 1 Rimini Street, Chaidari, 12462 Athens, Greece. madalamaga@med.uoa.gr |
Key Words |
Breast cancer; Obesity; Insulin resistance; Adipokines; Adiponectin; Resistin; Leptin; Nicotinamide phosphoribosyl-transferase; Visfatin |
Core Tip |
Recent evidence has shown that the constellation of obesity, insulin resistance and adipokines is associated with the risk and prognosis of postmenopausal breast cancer (BC). Direct evidence is growing rapidly supporting the stimulating and/or inhibiting role of adipokines in the process of development and progression of BC. Recent studies support a role of adipokines as novel risk factors and potential diagnostic and prognostic biomarkers in BC. This editorial aims at providing important insight into the potential pathophysiological mechanisms linking adipokines to the etiopathogenesis of BC in the context of a dysfunctional adipose tissue and insulin resistance in obesity. Understanding of these mechanisms may be important for the development of attractive preventive and therapeutic strategies against obesity-related breast malignancy. |
Publish Date |
2013-09-14 11:34 |
Citation |
Dalamaga M. Obesity, insulin resistance, adipocytokines and breast cancer: New biomarkers and attractive therapeutic targets. World J Exp Med 2013; 3(3): 34-42 |
URL |
http://www.wjgnet.com/2220-315X/full/v3/i3/34.htm |
DOI |
http://dx.doi.org/10.5493/wjem.v3.i3.34 |
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