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6/15/2018 9:13:16 AM | Browse: 248 | Download: 154
Publication Name World Journal of Gastroenterology
Manuscript ID 38560
Country/Territory China
2018-02-28 23:51
Peer-Review Started
2018-03-01 01:30
To Make the First Decision
2018-03-14 00:37
Return for Revision
2018-03-15 05:29
2018-03-27 09:09
Second Decision
2018-05-10 09:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-05-11 04:48
Articles in Press
2018-05-11 04:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-05-22 21:55
Typeset the Manuscript
2018-06-13 08:43
Publish the Manuscript Online
2018-06-15 09:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Microbiology
Manuscript Type Basic Study
Article Title Dynamic alterations in the gut microbiota and metabolome during the development of methionine-choline-deficient diet-induced nonalcoholic steatohepatitis
Manuscript Source Unsolicited Manuscript
All Author List Jian-Zhong Ye, Ya-Ting Li, Wen-Rui Wu, Ding Shi, Dai-Qiong Fang, Li-Ya Yang, Xiao-Yuan Bian, Jing-Jing Wu, Qing Wang, Xian-Wan Jiang, Cong-Gao Peng, Wan-Chun Ye, Peng-Cheng Xia and Lan-Juan Li
Author(s) ORCID Number
Jian-Zhong Ye http://orcid.org/0000-0001-8174-2580
Ya-Ting Li http://orcid.org/0000-0002-0761-4967
Wen-Rui Wu http://orcid.org/0000-0002-8457-9675
Ding Shi http://orcid.org/0000-0003-3988-9321
Dai-Qiong Fang http://orcid.org/0000-0002-0758-3988
Li-Ya Yang http://orcid.org/0000-0002-7832-983X
Xiao-Yuan Bian http://orcid.org/0000-0002-7275-3103
Jing-Jing Wu http://orcid.org/0000-0001-9289-0538
Qing Wang http://orcid.org/0000-0003-4914-5473
Xian-Wan Jiang http://orcid.org/0000-0003-0982-7306
Cong-Gao Peng http://orcid.org/0000-0002-0945-0986
Wan-Chun Ye http://orcid.org/0000-0002-2732-5150
Peng-Cheng Xia http://orcid.org/0000-0001-8990-4900
Lan-Juan Li http://orcid.org/0000-0001-6945-0593
Funding Agency and Grant Number
Funding Agency Grant Number
the National Natural Science Foundation of China No. 81330011
the National Natural Science Foundation of China No. 81790631
the National Natural Science Foundation of China No. 81790633
the Science Fund for Creative Research Groups of the National Natural Science Foundation of China No. 81121002
the National Basic Research Program of China (973 program) No. 2013CB531401
Corresponding author Lan-Juan Li, MD, PhD, Academic Research, Doctor, Professor, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, No.79 Qingchun Road, Hangzhou 310003, Zhejiang, China. ljli@zju.edu.cn
Keywords Nonalcoholic steatohepatitis; Methionine-choline deficient diet; Gut microbiota; Metabolome; Nonalcoholic fatty liver disease
Core Tip Nonalcoholic steatohepatitis (NASH) is increa­singly prevalent as a remarkable problem worldwide. Increased evidence indicates the critical role of gut microbiota in NASH progression. We aimed to investigate the dynamic alterations in the gut microbiota and the related metabolites during NASH development in mice fed a methionine-choline-deficient (MCD) diet. We for the first time find that the MCD diet may induce persistent gut microbiota and metabolome deterioration.
Publish Date 2018-06-15 09:13
Citation Ye JZ, Li YT, Wu WR, Shi D, Fang DQ, Yang LY, Bian XY, Wu JJ, Wang Q, Jiang XW, Peng CG, Ye WC, Xia PC, Li LJ. Dynamic alterations in the gut microbiota and metabolome during the development of methionine-choline-deficient diet-induced nonalcoholic steatohepatitis. World J Gastroenterol 2018; 24(23): 2468-2481
Url http://www.wjgnet.com/1007-9327/full/v24/i23/2468.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i23.2468
Full Article (PDF) WJG-24-2468.pdf
Full Article (Word) WJG-24-2468.doc
Manuscript File 38560-Review.docx
Answering Reviewers 38560-Answering reviewers.pdf
Audio Core Tip 38560-Audio core tip.m4a
Biostatistics Review Certificate 38560-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 38560-Conflict-of-interest statement.pdf
Copyright License Agreement 38560-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 38560-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 38560-Animal care and use statement.pdf
Institutional Review Board Approval Form or Document 38560-Institutional-Review-Board-Approval-Form-or-Document-revision.pdf
Non-Native Speakers of English Editing Certificate 38560-Language certificate.pdf
Supplementary Material 38560-Supplementary material.pdf
Peer-review Report 38560-Peer-review(s).pdf
Scientific Misconduct Check 38560-Scientific misconduct check.pdf
Scientific Editor Work List 38560-Scientific editor work list.pdf